Global burden of Clostridium difficile infections: a systematic review and meta-analysis

E Balsells, T Shi, C Leese, I Lyell… - Journal of global …, 2018 - pmc.ncbi.nlm.nih.gov
Background Clostridium difficile is a leading cause of morbidity and mortality in several
countries. However, there are limited evidence characterizing its role as a global public …

The risks of long-term use of proton pump inhibitors: a critical review

M Jaynes, AB Kumar - Therapeutic advances in drug safety, 2019 - journals.sagepub.com
Proton pump inhibitors (PPIs) are among the most frequently prescribed medications. Their
use is likely even higher than estimated due to an increase in the number of PPIs available …

[HTML][HTML] Proton pump inhibitors therapy and risk of Clostridium difficile infection: Systematic review and meta-analysis

A Trifan, C Stanciu, I Girleanu, OC Stoica… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs)
therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a …

Prevalence and outcome of gastrointestinal bleeding and use of acid suppressants in acutely ill adult intensive care patients

M Krag, A Perner, J Wetterslev, MP Wise… - Intensive care …, 2015 - Springer
Purpose To describe the prevalence of, risk factors for, and prognostic importance of
gastrointestinal (GI) bleeding and use of acid suppressants in acutely ill adult intensive care …

Prophylaxis against upper gastrointestinal bleeding in hospitalized patients

D Cook, G Guyatt - New England Journal of Medicine, 2018 - Mass Medical Soc
Preventing Gastrointestinal Bleeding in the Hospital Acid suppression is widely used to
lower the risk of gastrointestinal bleeding in critically ill patients, and the practice has spread …

Updated meta-analysis of controlled observational studies: proton-pump inhibitors and risk of Clostridium difficile infection

F Cao, CX Chen, M Wang, HR Liao, MX Wang… - Journal of Hospital …, 2018 - Elsevier
Attention has recently been directed toward a plausible link between Clostridium difficile
infection (CDI) and proton-pump inhibitors (PPIs). However, the results of studies on the …

Stress ulcer prophylaxis

JF Barletta, JJ Bruno, MS Buckley… - Critical care medicine, 2016 - journals.lww.com
Objectives: Stress ulcer prophylaxis is commonly administered to critically ill patients for the
prevention of clinically important stress-related mucosal bleeding from the upper …

[HTML][HTML] Guidelines for antibiotic prescription in intensive care unit

GC Khilnani, K Zirpe, V Hadda, Y Mehta… - Indian journal of …, 2019 - ncbi.nlm.nih.gov
How to cite this article: Khilnani GC, Zirpe K, Hadda V, Mehta Y, Madan K, Kulkarni A,
Mohan A, Dixit S, Guleria R, Bhattacharya P. Guidelines for Antibiotic Prescription in …

Proton-Pump Inhibitors to Prevent Gastrointestinal Bleeding—An Updated Meta-Analysis

Y Wang, S Parpia, L Ge, D Heels-Ansdell, H Lai… - NEJM …, 2024 - evidence.nejm.org
Background The goal of this systematic review was to examine the efficacy and safety of
proton-pump inhibitors for stress ulcer prophylaxis in critically ill patients. Methods We …

Clostridium difficile Infection and Fecal Microbiota Transplant

A Liubakka, BP Vaughn - AACN advanced critical care, 2016 - AACN
Clostridium difficile infection (CDI) is a major source of morbidity and mortality for
hospitalized patients. Although most patients have a clinical response to existing …