Neoteric deep eutectic solvents: history, recent developments, and catalytic applications

M Shaibuna, LV Theresa, K Sreekumar - Soft Matter, 2022 - pubs.rsc.org
Deep eutectic solvents (DESs) are modified versions of ionic liquids (ILs) and are formed by
the fusion of polar components (liquids or solids) via hydrogen bonding interactions. DESs …

Brain delivery of curcumin through low-intensity ultrasound-induced blood–brain barrier opening via lipid-plga nanobubbles

Y Yan, Y Chen, Z Liu, F Cai, W Niu, L Song… - International Journal …, 2021 - Taylor & Francis
Background Parkinson's disease (PD) is a progressive neurodegenerative disorder. Owing
to the presence of blood–brain barrier (BBB), conventional pharmaceutical agents are …

Development of the amorphous solid dispersion of curcumin: a rational selection of polymers for enhanced solubility and dissolution

M Ishtiaq, S Asghar, IU Khan, MS Iqbal, SH Khalid - Crystals, 2022 - mdpi.com
The goal of this investigation was to determine the effectiveness of hydrophilic polymers in
preparing a solid dispersion to enhance the solubility and dissolution of poorly water-soluble …

Saquinavir-Piperine Eutectic Mixture: Preparation, Characterization, and Dissolution Profile

C Fandaruff, MI Quirós-Fallas, JR Vega-Baudrit… - Pharmaceutics, 2023 - mdpi.com
The dissolution rate of the anti-HIV drug saquinavir base (SQV), a poorly water-soluble and
extremely low absolute bioavailability drug, was improved through a eutectic mixture …

Solubility improvement of curcumin with amino acids

A Gunnam, AK Nangia - CrystEngComm, 2021 - pubs.rsc.org
Curcumin (CUR) is used as a dietary and food supplement with medicinal properties. It has
a wide range of therapeutic activities such as antioxidant, anti-inflammatory, anti-arthritis …

Exploiting hydrogen bonding to enhance lidocaine loading and stability in a poly ethylene-co-vinyl acetate carrier matrix

P Agarwal, MK Nieuwoudt, S Li, G Procter… - International Journal of …, 2022 - Elsevier
Sustained release of lidocaine from poly ethylene-co-vinyl acetate (EVA) implants can
significantly improve pain management outcomes; however, poor drug loading is a major …

Molecular insights into warfarin sodium 2-propanol solvate solid form changes and disproportionation using a low volume two-stage dissolution approach

HS Shah, K Chaturvedi, RH Dave… - Molecular …, 2021 - ACS Publications
The current research work focuses on understanding the reported discrepancies and our
observations in the dissolution profiles of warfarin sodium tablets and potential patient …

Design of ascorbic acid eutectic mixtures with sugars to inhibit oxidative degradation

V Palanisamy, P Sanphui, K Palanisamy… - Frontiers in …, 2022 - frontiersin.org
L-Ascorbic acid (ASC), commonly known as vitamin C, acts as an anti-oxidant in the
biological system. It is extensively used as an excipient in pharmaceutical industry, food …

Optimization of a Twin screw melt granulation process for fixed dose combination immediate release Tablets: Differential amorphization of one drug and crystalline …

SR Munnangi, N Narala, P Lakkala, SK Vemula… - International Journal of …, 2024 - Elsevier
Abstract Interest in Twin Screw Melt Granulation (TSMG) processes is rapidly increasing,
along with the search for suitable excipients. This study aims to optimize the TSMG process …

Pharmacotechnical evaluation by SeDem Expert system to develop Orodispersible tablets

MRP Rao, S Sapate, A Sonawane - AAPS PharmSciTech, 2022 - Springer
Sediment delivery model (SeDeM) system is innovative tool to correlate micromeritic
properties of powders with compressibility. It involves computation of indices which facilitate …