Combinatorial metabolic pathway assembly approaches and toolkits for modular assembly

R Young, M Haines, M Storch, PS Freemont - Metabolic Engineering, 2021 - Elsevier
Synthetic Biology is a rapidly growing interdisciplinary field that is primarily built upon
foundational advances in molecular biology combined with engineering design principles …

[HTML][HTML] Digital microfluidics as an emerging tool for bacterial protocols

CR Nemr, AA Sklavounos, AR Wheeler, SO Kelley - SLAS technology, 2023 - Elsevier
Bacteria are widely studied in various research areas, including synthetic biology,
sequencing and diagnostic testing. Protocols involving bacteria are often multistep …

Automated miniaturized digital microfluidic antimicrobial susceptibility test using a chip-integrated optical oxygen sensor

W Qiu, S Nagl - ACS sensors, 2021 - ACS Publications
We present the first digital microfluidic (DMF) antimicrobial susceptibility test (AST) using an
optical oxygen sensor film for in-situ and real-time continuous measurement of extracellular …

Digital microfluidic thermal control chip-based multichannel immunosensor for noninvasively detecting acute myocardial infarction

J Shen, L Zhang, J Yuan, Y Zhu, H Cheng… - Analytical …, 2021 - ACS Publications
Rapid and automated detection of acute myocardial infarction (AMI) at its developing stage
is very important due to its high mortality rate. To quantitatively diagnose AMI, Myo, CK-MB …

Integrating machine learning and digital microfluidics for screening experimental conditions

F Ahmadi, M Simchi, JM Perry, S Frenette, H Benali… - Lab on a Chip, 2023 - pubs.rsc.org
Digital microfluidics (DMF) has the signatures of an ideal liquid handling platform–as shown
through almost two decades of automated biological and chemical assays. However, in the …

Role of digital microfluidics in enabling access to laboratory automation and making biology programmable

VB Kothamachu, S Zaini… - … Translating Life Sciences …, 2020 - journals.sagepub.com
Digital microfluidics (DMF) is a liquid handling technique that has been demonstrated to
automate biological experimentation in a low-cost, rapid, and programmable manner. This …

A Tri‐Droplet Liquid Structure for Highly Efficient Intracellular Delivery in Primary Mammalian Cells Using Digital Microfluidics

SR Little, Z Leung, ABV Quach… - Advanced Materials …, 2023 - Wiley Online Library
Automated techniques for mammalian cell engineering are needed to examine a wide range
of unique genetic perturbations especially when working with precious patient samples. An …

Designing splicing digital microfluidics chips based on polytetrafluoroethylene membrane

H Feng, Z Yi, R Yang, X Qin, S Shen, W Zeng, L Shui… - Micromachines, 2020 - mdpi.com
As a laboratory-on-a-chip application tool, digital microfluidics (DMF) technology is widely
used in DNA-based applications, clinical diagnosis, chemical synthesis, and other fields …

An evolutionary algorithm with indirect representation for droplet routing in digital microfluidic biochips

C Jiang, RQ Yang, B Yuan - Engineering Applications of Artificial …, 2022 - Elsevier
As a revolutionary platform for miniaturizing laboratory procedures, the digital microfluidic
biochip (DMFB) has the advantages of flexibility and re-configurability over its flow-based …

Automated Droplet Ejection from a Digital Microfluidics Sample Pretreatment Device Enables Batch-Mode Chemiluminescence Immunoassay

D Huang, E Huang, D Cai, Z Chen, H Wen… - Analytical …, 2024 - ACS Publications
Digital microfluidics (DMF) features programmed manipulation of fluids in multiple steps,
making it a valuable tool for sample pretreatment. However, the integration of sample …