Opium, the dried juice of the seedpod of the opium poppy, has been used for the relief of pain and suffering for several thousand years. Many opioid drugs are still derived from …
Cervical cancer is one of the gravest threats to women's lives. It is estimated that over a million women worldwide currently have cervical cancer. Most of these women have not …
R Chou, GJ Fanciullo, PG Fine, JA Adler… - The journal of pain, 2009 - Elsevier
Use of chronic opioid therapy for chronic noncancer pain has increased substantially. The American Pain Society and the American Academy of Pain Medicine commissioned a …
JC Ballantyne, NS Shin - The Clinical journal of pain, 2008 - journals.lww.com
Opioid therapy for chronic pain has been popularized over the past few decades, and a concern has arisen that the analgesic efficacy of opioids is not always maintained over …
Despite the increasing clinical use of transdermal buprenorphine, questions have persisted about the possibility of a ceiling effect for analgesia, its combination with other μ‐opioid …
AM Drewes, RD Jensen, LM Nielsen… - British journal of …, 2013 - Wiley Online Library
Clinical studies comparing the response and side effects of various opioids have not been able to show robust differences between drugs. Hence, recommendations of the regulatory …
MJ Simoff, B Lally, MG Slade, WG Goldberg, P Lee… - Chest, 2013 - Elsevier
Background Many patients with lung cancer will develop symptoms related to their disease process or the treatment they are receiving. These symptoms can be as debilitating as the …
C Rivat, J Ballantyne - Pain reports, 2016 - journals.lww.com
Objectives: We aimed to examine the published literature on basic science explaining pronociceptive opioid actions, and apply this knowledge to clinical observation. Methods …
SE Harrington, TJ Smith - Jama, 2008 - jamanetwork.com
Patients face difficult decisions about chemotherapy near the end of life. Such treatment might prolong survival or reduce symptoms but cause adverse effects, prevent the patient …