The microbiome plays a fundamental role in the maturation, function, and regulation of the
host-immune system from birth to old age. In return, the immune system has co-evolved a …

The microbiota plays an essential role in the education, development, and function of the
immune system, both locally and systemically. Emerging experimental and epidemiological …

The relationship between gut microbial dysbiosis and acute or chronic kidney disease
(CKD) is still unclear. Here, we show that oral administration of the probiotic Lactobacillus …

Inflammation is an evolutionarily selected defense response to infection or tissue damage
that involves activation and consumption of immune cells in order to reestablish and …

The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …

As the intestinal microbiota has become better appreciated as necessary for maintenance of
physiologic homeostasis and also as a modulator of disease processes, there has been a …

Crosstalk between the gut microbiota and the host has attracted considerable attention
owing to its involvement in diverse diseases. Chronic kidney disease (CKD) is commonly …

The unprecedented increase of life expectancy challenges society to protect the elderly from
morbidity and mortality making vaccination a crucial mean to safeguard this population …

Hematopoietic stem cells (HSCs) are responsible for lifelong production of blood cells. At the
same time, they must respond rapidly to acute needs such as infection or injury. Significant …

Hematopoietic stem cell (HSC) aging is accompanied by hematopoietic reconstitution
dysfunction, including loss of regenerative and engraftment ability, myeloid differentiation …