Psychedelics

DE Nichols - Pharmacological reviews, 2016 - ASPET
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

Episodic memory in normal aging and Alzheimer disease: Insights from imaging and behavioral studies

D Tromp, A Dufour, S Lithfous, T Pebayle… - Ageing research …, 2015 - Elsevier
Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …

The role of serotonin 5-HT2A receptors in memory and cognition

G Zhang, RW Stackman Jr - Frontiers in pharmacology, 2015 - frontiersin.org
Serotonin 5-HT2A receptors (5-HT2ARs) are widely distributed in the central nervous
system, especially in brain region essential for learning and cognition. In addition to …

Serotonin modulation of cortical neurons and networks

P Celada, MV Puig, F Artigas - Frontiers in integrative neuroscience, 2013 - frontiersin.org
The serotonergic pathways originating in the dorsal and median raphe nuclei (DR and MnR,
respectively) are critically involved in cortical function. Serotonin (5-HT), acting on …

Expression of Serotonin1A and Serotonin2A Receptors in Pyramidal and GABAergic Neurons of the Rat Prefrontal Cortex

N Santana, A Bortolozzi, J Serrats, G Mengod… - Cerebral …, 2004 - academic.oup.com
Abstract Serotonergic 5-HT1A and 5-HT2A receptors are abundantly expressed in prefrontal
cortex (PFC) and are targets of atypical antipsychotic drugs. They mediate, respectively …

Common Kibra Alleles Are Associated with Human Memory Performance

A Papassotiropoulos, DA Stephan, MJ Huentelman… - Science, 2006 - science.org
Human memory is a polygenic trait. We performed a genome-wide screen to identify
memory-related gene variants. A genomic locus encoding the brain protein KIBRA was …

Genes and the parsing of cognitive processes

TE Goldberg, DR Weinberger - Trends in cognitive sciences, 2004 - cell.com
Now that the human genome has been sequenced there exists the possibility of identifying
specific genes that affect human cognition. In this article, recent studies that have found …

Better Memory and Neural Efficiency in Young Apolipoprotein E ε4 Carriers

CRA Mondadori, DJF de Quervain, A Buchmann… - Cerebral …, 2007 - academic.oup.com
The apolipoprotein E (APOE) ε4 allele is the major genetic risk factor for Alzheimer's
disease, but an APOE effect on memory performance and memory-related neurophysiology …

Modulation of the Activity of Pyramidal Neurons in Rat Prefrontal Cortex by Raphe Stimulation In Vivo: Involvement of Serotonin and GABA

MV Puig, F Artigas, P Celada - Cerebral Cortex, 2005 - academic.oup.com
Serotonin is involved in psychiatric disorders exhibiting abnormal prefrontal cortex (PFC)
function (eg major depression, schizophrenia). We examined the effect of the stimulation of …

Individual differences in anxiety trait are related to spatial learning abilities and hippocampal expression of mineralocorticoid receptors

AI Herrero, C Sandi, C Venero - Neurobiology of learning and memory, 2006 - Elsevier
Although high levels of anxiety might be expected to negatively influence learning and
memory, it remains to be shown whether individual differences in anxiety may influence …