Tetrodotoxin: Chemistry, toxicity, source, distribution and detection

V Bane, M Lehane, M Dikshit, A O'Riordan, A Furey - Toxins, 2014 - mdpi.com
Tetrodotoxin (TTX) is a naturally occurring toxin that has been responsible for human
intoxications and fatalities. Its usual route of toxicity is via the ingestion of contaminated …

The molecular mystique of tetrodotoxin

EG Moczydlowski - Toxicon, 2013 - Elsevier
In many respects tetrodotoxin (TTX) is the quintessential natural toxin. It is unequivocally
toxic to mammals with LD50 values for mice in the range of 10 μg/kg (intraperitoneal), 16 …

New gastropod vectors and tetrodotoxin potential expansion in temperate waters of the Atlantic Ocean

M Silva, J Azevedo, P Rodriguez, A Alfonso, LM Botana… - Marine drugs, 2012 - mdpi.com
Tetrodotoxin is a potent low weight marine toxin found in warm waters, especially of the
Indian and Pacific Oceans. Intoxications are usually linked to the consumption of the puffer …

Tetrodotoxins occurrence in non-traditional vectors of the north atlantic waters (Portuguese maritime territory, and morocco coast)

M Silva, I Rodríguez, A Barreiro, M Kaufmann, AI Neto… - Toxins, 2019 - mdpi.com
Tetrodotoxin (TTX) is a potent alkaloid typically from tropical ecosystems, but in the last
decade its presence has been more pronounced in the temperate waters of the Atlantic. In …

Toxicology of seafood toxins: A critical review

R Munday - Seafood and Freshwater Toxins: Pharmacology …, 2014 - api.taylorfrancis.com
Since earliest times, human food has been contaminated with bioactive substances. These
may be derived from plants, such as solanine in green potatoes or the cyanide in cassava …

The incidence of tetrodotoxin and its analogs in the Indian Ocean and the Red Sea

IJ Tamele, M Silva, V Vasconcelos - Marine drugs, 2019 - mdpi.com
Tetrodotoxin (TTX) is a potent marine neurotoxin with bacterial origin. To date, around 28
analogs of TTX are known, but only 12 were detected in marine organisms, namely TTX, 11 …

LC-MS/MS method for the determination of tetrodotoxin (TTX) on a triple quadruple mass spectrometer

V Bane, S Hutchinson, A Sheehan… - Food Additives & …, 2016 - Taylor & Francis
Tetrodotoxin (TTX), often referred to as the 'puffer fish'poison, is a marine toxin and it has
been identified as the agent responsible for many food poisoning incidents around the …

Intra-organismal distribution of tetrodotoxin in two species of blue-ringed octopuses (Hapalochlaena fasciata and H. lunulata)

BL Williams, RL Caldwell - Toxicon, 2009 - Elsevier
In-depth studies on the intra-organismal distribution of toxin may yield valuable clues about
potential ecological functions. The distribution of tetrodotoxin (TTX) in previously …

Immunoaffinity chromatography purification and ultrahigh performance liquid chromatography tandem mass spectrometry determination of tetrodotoxin in marine …

X Zhang, Z Yan, Y Wang, T Jiang, J Wang… - Journal of agricultural …, 2015 - ACS Publications
A highly selective and sensitive method was developed for the determination of tetrodotoxin
(TTX) in marine organisms by immunoaffinity chromatography (IAC) purification coupled with …

Occurrence of tetrodotoxin and paralytic shellfish poisons in a gastropod implicated in food poisoning in southern Taiwan

HC Jen, SJ Lin, SY Lin, YW Huang, IC Liao… - Food additives and …, 2007 - Taylor & Francis
The toxicity of the gastropod Nassarius papillosus implicated in a food paralytic poisoning
incident in Liuchiu Island, Taiwan, in October 2005 is reported. The symptoms of a victim (67 …