Post-COVID syndrome: an insight on its pathogenesis

HC Maltezou, A Pavli, A Tsakris - Vaccines, 2021 - mdpi.com
Post-COVID syndrome is increasingly recognized as a new clinical entity in the context of
SARS-CoV-2 infection. Symptoms persisting for more than three weeks after the diagnosis of …

Single-cell immunology of SARS-CoV-2 infection

Y Tian, LN Carpp, HER Miller, M Zager… - Nature …, 2022 - nature.com
Gaining a better understanding of the immune cell subsets and molecular factors associated
with protective or pathological immunity against severe acute respiratory syndrome …

Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets

RM Cox, JD Wolf, CM Lieber, J Sourimant… - Nature …, 2021 - nature.com
Remdesivir is an antiviral approved for COVID-19 treatment, but its wider use is limited by
intravenous delivery. An orally bioavailable remdesivir analog may boost therapeutic benefit …

[HTML][HTML] SARS-CoV-2 (COVID-19), viral load and clinical outcomes; lessons learned one year into the pandemic: a systematic review

S Shenoy - World Journal of Critical Care Medicine, 2021 - ncbi.nlm.nih.gov
BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections
is diagnosed via real time reverse transcriptase polymerase chain reaction (RT-PCR) and …

Possible use of phytochemicals for recovery from COVID-19-induced anosmia and ageusia

S Koyama, K Kondo, R Ueha, H Kashiwadani… - International Journal of …, 2021 - mdpi.com
The year 2020 became the year of the outbreak of coronavirus, SARS-CoV-2, which
escalated into a worldwide pandemic and continued into 2021. One of the unique symptoms …

SARS-CoV-2 viral-load distribution reveals that viral loads increase with age: a retrospective cross-sectional cohort study

S Euser, S Aronson, I Manders… - International journal …, 2021 - academic.oup.com
Abstract Background Describing the SARS-CoV-2 viral-load distribution in different patient
groups and age categories. Methods All results from first nasopharyngeal (NP) and …

[HTML][HTML] A real-life setting evaluation of the effect of remdesivir on viral load in COVID-19 patients admitted to a large tertiary centre in Israel

E Goldberg, HB Zvi, L Sheena, S Sofer, I Krause… - Clinical Microbiology …, 2021 - Elsevier
Objectives The effectiveness of remdesivir, a Food and Drug Administration-approved drug
for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has been repeatedly …

Mechanisms contributing to adverse outcomes of COVID-19 in obesity

M Sudhakar, SB Winfred, G Meiyazhagan… - Molecular and cellular …, 2022 - Springer
A growing amount of epidemiological data from multiple countries indicate an increased
prevalence of obesity, more importantly central obesity, among hospitalized subjects with …

Association between SARS-CoV-2 cycle threshold values and clinical outcomes in patients with COVID-19: a systematic review and meta-analysis

VP Shah, WH Farah, JC Hill, LC Hassett… - Open forum …, 2021 - academic.oup.com
Cycle threshold (CT) values are correlated with the amount of viral nucleic acid in a sample
and may be obtained from some qualitative real-time polymerase chain reaction tests used …

Household transmission of severe acute respiratory syndrome coronavirus 2 in the United States: living density, viral load, and disproportionate impact on …

C Cerami, ZR Popkin-Hall, T Rapp… - Clinical Infectious …, 2022 - academic.oup.com
Background Households are hot spots for severe acute respiratory syndrome coronavirus 2
transmission. Methods This prospective study enrolled 100 coronavirus disease 2019 …