The evolution of resistance to synergistic multi‐drug combinations is more complex than evolving resistance to each individual drug component
NA Lozano‐Huntelman, A Bullivant… - Evolutionary …, 2023 - Wiley Online Library
Multidrug antibiotic resistance is an urgent public health concern. Multiple strategies have
been suggested to alleviate this problem, including the use of antibiotic combinations and …
been suggested to alleviate this problem, including the use of antibiotic combinations and …
Meta-analysis of three-stressor combinations on population-level fitness reveal substantial higher-order interactions
ES Diamant, S Boyd, NA Lozano-Huntelman… - Science of The Total …, 2023 - Elsevier
Although natural populations are typically subjected to multiple stressors, most past
research has focused on single-stressor and two-stressor interactions, with little attention …
research has focused on single-stressor and two-stressor interactions, with little attention …
Environment by environment interactions (ExE) differ across genetic backgrounds (ExExG)
K Schmidlin, CB Ogbunugafor, S Alexander… - …, 2024 - pmc.ncbi.nlm.nih.gov
While the terms “gene-by-gene interaction”(GxG) and “gene-by-environment
interaction”(GxE) are widely recognized in the fields of quantitative and evolutionary …
interaction”(GxE) are widely recognized in the fields of quantitative and evolutionary …
[图书][B] PKPD-Model Based Preclinical Characterization of the Activity of Spectinamide 1599 Against Mycobacterial Subpopulations and the Identification of Potential …
ZH Temrikar - 2023 - search.proquest.com
Tuberculosis is one of the top 10 causes of death worldwide and the leading cause of death
from a single infectious agent prior to COVID19. Mycobacterium tuberculosis (Mtb) is the …
from a single infectious agent prior to COVID19. Mycobacterium tuberculosis (Mtb) is the …