Fundamentals and applications of inertial microfluidics: A review

J Zhang, S Yan, D Yuan, G Alici, NT Nguyen… - Lab on a Chip, 2016 - pubs.rsc.org
In the last decade, inertial microfluidics has attracted significant attention and a wide variety
of channel designs that focus, concentrate and separate particles and fluids have been …

Inertial microfluidic physics

H Amini, W Lee, D Di Carlo - Lab on a Chip, 2014 - pubs.rsc.org
Microfluidics has experienced massive growth in the past two decades, and especially with
advances in rapid prototyping researchers have explored a multitude of channel structures …

Ultra-fast, label-free isolation of circulating tumor cells from blood using spiral microfluidics

ME Warkiani, BL Khoo, L Wu, AKP Tay, AAS Bhagat… - Nature protocols, 2016 - nature.com
Circulating tumor cells (CTCs) are rare cancer cells that are shed from primary or metastatic
tumors into the peripheral blood circulation. Phenotypic and genetic characterization of …

Inertial focusing in microfluidics

JM Martel, M Toner - Annual review of biomedical engineering, 2014 - annualreviews.org
When Segré and Silberberg in 1961 witnessed particles in a laminar pipe flow congregating
at an annulus in the pipe, scientists were perplexed and spent decades learning why such …

Fundamentals of inertial focusing in microchannels

J Zhou, I Papautsky - Lab on a Chip, 2013 - pubs.rsc.org
Inertial microfluidics has been attracting considerable interest in recent years due to
immensely promising applications in cell biology. Despite the intense attention, the primary …

Spiral microchannel with rectangular and trapezoidal cross-sections for size based particle separation

G Guan, L Wu, AA Bhagat, Z Li, PCY Chen, S Chao… - Scientific reports, 2013 - nature.com
The paper reports a new method for three-dimensional observation of the location of
focused particle streams along both the depth and width of the channel cross-section in …

Hydrodynamic mechanisms of cell and particle trapping in microfluidics

A Karimi, S Yazdi, AM Ardekani - Biomicrofluidics, 2013 - pubs.aip.org
Focusing and sorting cells and particles utilizing microfluidic phenomena have been
flourishing areas of development in recent years. These processes are largely beneficial in …

A review of secondary flow in inertial microfluidics

Q Zhao, D Yuan, J Zhang, W Li - Micromachines, 2020 - mdpi.com
Inertial microfluidic technology, which can manipulate the target particle entirely relying on
the microchannel characteristic geometry and intrinsic hydrodynamic effect, has attracted …

Inertial focusing of spherical particles in rectangular microchannels over a wide range of Reynolds numbers

C Liu, G Hu, X Jiang, J Sun - Lab on a Chip, 2015 - pubs.rsc.org
Inertial microfluidics has emerged as an important tool for manipulating particles and cells.
For a better design of inertial microfluidic devices, we conduct 3D direct numerical …

Continuous separation of microparticles in a microfluidic channel via the elasto-inertial effect of non-Newtonian fluid

J Nam, H Lim, D Kim, H Jung, S Shin - Lab on a Chip, 2012 - pubs.rsc.org
Pure separation and sorting of microparticles from complex fluids are essential for
biochemical analyses and clinical diagnostics. However, conventional techniques require …