The lipid droplet (LD) is an organelle enveloped by a monolayer phospholipid membrane
with a core of neutral lipids, which is conserved from bacteria to humans. The available …

Background Increased fructose intake has been associated with metabolic consequences
such as impaired hepatic lipid metabolism and development of nonalcoholic fatty liver …

Acetylcarnitine is an essential metabolite for maintaining metabolic flexibility and glucose
homeostasis. The in vivo behavior of muscle acetylcarnitine content during exercise has not …

Intramyocellular lipid (IMCL) accumulation has been linked to both insulin-resistant and
insulin-sensitive (athletes) states. Biochemical analysis of intramuscular triglyceride …

Imaging skeletal muscle function and metabolism, as reported by local hemodynamics and
oxygen kinetics, can elucidate muscle performance, severity of an underlying disease or …

Patients with active acromegaly (ACRO) exhibit low hepatocellular lipids (HCL), despite
pronounced insulin resistance (IR). This contrasts the strong association of IR with …

Most in vivo 31P MR studies are realized on 3T MR systems that provide sufficient signal
intensity for prominent phosphorus metabolites. The identification of these metabolites in the …

The prevalence of obesity and metabolic syndrome increases in patients with type 1
diabetes mellitus (T1DM). In the general population this is linked with ectopic lipid …

Many cells adapt to hyperosmolal conditions by upregulation of organic osmolytes to
maintain cell function and integrity. Glycerophosphocholine (GPC), a recognized osmolyte in …

Background Daily nutrition plays an important role in supporting training adaptions and
endurance performance. The objective of this 10-week study was to investigate the …