J Bossuyt, Y Van Den Herrewegen, L Nestor, A Buckinx… - Glia, 2023 - Wiley Online Library
Insights into the role astrocytes and microglia play in normal and diseased brain functioning has expanded drastically over the last decade. Recently, chemogenetic tools have emerged …
LM Holt, EJ Nestler - Journal of Neural Transmission, 2024 - Springer
Addiction is a leading cause of disease burden worldwide and remains a challenge in current neuroscience research. Drug-induced lasting changes in gene expression are …
M Corkrum, A Araque - Neuropsychopharmacology, 2021 - nature.com
Astrocytes are fundamental components of brain information processing and possess the ability to respond to synaptic signaling with increases in cytoplasmic calcium and modulate …
Recent evidence suggests that alcohol use disorder (AUD) may manifest itself differently in women compared to men. Women experience AUDs on an accelerated timeline and may …
CD Walker, HG Sexton, J Hyde, B Greene, ML Risher - Cells, 2022 - mdpi.com
Adolescence is a developmental period that encompasses, but is not limited to, puberty and continues into early adulthood. During this period, maturation and refinement are observed …
Chemogenetics enables precise, non-invasive, and reversible modulation of neural activity via the activation of engineered receptors that are pharmacologically selective to …
Adolescent alcohol abuse is a significant public health concern, with approximately 4.3 million US adolescents reporting monthly binge drinking. Excessive ethanol consumption …
E Shigetomi, S Koizumi - Neuroscience Research, 2023 - Elsevier
Astrocytes are present throughout the brain and intimately interact with neurons and blood vessels. Three decades of research have shown that astrocytes reciprocally communicate …
DL Gruol, D Calderon, K French, C Melkonian… - …, 2023 - Elsevier
The neuroimmune system of the brain, which is comprised primarily of astrocytes and microglia, regulates a variety of homeostatic mechanisms that underlie normal brain …