ABSTRACT A common, long‐held belief is that metabolic rate drives the rates of various biological, ecological and evolutionary processes. Although this metabolic pacemaker view …
T Garland Jr, CJ Downs… - … and biochemical zoology, 2022 - journals.uchicago.edu
Trade-offs and constraints are inherent to life, and studies of these phenomena play a central role in both organismal and evolutionary biology. Trade-offs can be defined …
All organisms have a stress response system to cope with environmental threats, yet its precise form varies hugely within and across individuals, populations, and species. While …
Fluctuations in abiotic and biotic conditions exist in almost all habitats (Dunlap, Loros, & DeCoursey, 2004; Stevenson et al., 2015). Some fluctuations like the alternation between …
Extended bouts of fasting are ingrained in the ecology of many organisms, characterizing aspects of reproduction, development, hibernation, estivation, migration, and infrequent …
AA Cohen - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2018 - Elsevier
Use of model organisms in aging research is problematic because our ability to extrapolate across the tree of life is not clear. On one hand, there are conserved pathways that regulate …
An increasing number of aging researchers believes that multi‐system physiological dysregulation may be a key biological mechanism of aging, but evidence of this has been …
Coping with perturbations of the environment such as severe storms and other climatic extremes, habitat degradation, changes in predator numbers, invasive species and social …
AA Cohen, E Milot, J Yong, CL Seplaki, T Fülöp… - Mechanisms of ageing …, 2013 - Elsevier
Previous studies have identified many biomarkers that are associated with aging and related outcomes, but the relevance of these markers for underlying processes and their …