Esophageal cancer (EC) seriously threatens human health, and a promising new avenue for
EC treatment involves cancer immunotherapy. To improve the efficacy of EC immunotherapy …

Background To analyze the relationship between tumor-infiltrating lymphocytes (TILs)
subtypes and infiltration locations and the prognosis of gastric cancer (GC) patients …

Objective: The aim of this study was to determine the clinical role of the systemic immune-
inflammation index in patients with resectable adenocarcinoma of the gastroesophageal …

Immune checkpoints are accessory molecules that either promote or inhibit T-cell activation.
Two inhibitory molecules, cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell …

Gastroesophageal cancers (GOCs) represent some of the most common cancers globally
and are linked with poor survival rates. The current standard of care includes multimodal …

In order to explore the potential of immune checkpoint blockade in sarcoma, we investigated
expression and clinical relevance of programmed cell death-1 (PD-1), programmed death …

Monoclonal antibodies (abs) targeting the programmed cell death 1 (PD-1) immune
checkpoint pathway have revolutionized tumor therapy. Because T-cell-directed PD-1 …

Esophageal cancer remains a global health concern with a dismal prognosis and an
estimated 5-year survival rate of approximately 10–15%. Immunotherapy is a novel …

ABSTRACT Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell
lymphoma (L-CTCL) that arises from malignant clonally derived skin-homing CD4+ T cells …

Background In colorectal cancer (CRC), the indication for immune checkpoint inhibitors is
determined by the microsatellite instability status of the tumors. However, an optimal …