DNA architecture: from G to Z

AT Phan, V Kuryavyi, DJ Patel - Current opinion in structural biology, 2006 - Elsevier
G-quadruplexes and Z-DNA are two important non-B forms of DNA architecture. Results on
novel structural elements, folding and unfolding kinetics, and interactions with small …

A metallo-DNA nanowire with uninterrupted one-dimensional silver array

J Kondo, Y Tada, T Dairaku, Y Hattori, H Saneyoshi… - Nature …, 2017 - nature.com
The double-helix structure of DNA, in which complementary strands reversibly hybridize to
each other, not only explains how genetic information is stored and replicated, but also has …

Crystallographic studies of quadruplex nucleic acids

NH Campbell, GN Parkinson - Methods, 2007 - Elsevier
DNA quadruplexes are formed from guanine-rich repeats that self-associate into higher
order four-stranded structures. These G-rich repeat sequences can be found in both …

Role of alkali metal ions in G-quadruplex nucleic acid structure and stability

E Largy, JL Mergny, V Gabelica - The alkali metal ions: Their role for life, 2016 - Springer
G-quadruplexes are guanine-rich nucleic acids that fold by forming successive quartets of
guanines (the G-tetrads), stabilized by intra-quartet hydrogen bonds, inter-quartet stacking …

DNA conformations and their sequence preferences

D Svozil, J Kalina, M Omelka… - Nucleic Acids …, 2008 - academic.oup.com
The geometry of the phosphodiester backbone was analyzed for 7739 dinucleotides from
447 selected crystal structures of naked and complexed DNA. Ten torsion angles of a near …

Guanine base stacking in G-quadruplex nucleic acids

CJ Lech, B Heddi, AT Phan - Nucleic acids research, 2013 - academic.oup.com
G-quadruplexes constitute a class of nucleic acid structures defined by stacked guanine
tetrads (or G-tetrads) with guanine bases from neighboring tetrads stacking with one another …

Direct NMR detection of alkali metal ions bound to G-quadruplex DNA

R Ida, G Wu - Journal of the American Chemical Society, 2008 - ACS Publications
We describe a general multinuclear (1H, 23Na, 87Rb) NMR approach for direct detection of
alkali metal ions bound to G-quadruplex DNA. This study is motivated by our recent …

Chiral sum frequency generation spectroscopy detects double-helix dna at interfaces

EA Perets, KB Olesen, ECY Yan - Langmuir, 2022 - ACS Publications
Many DNA-based technologies involve the immobilization of DNA and therefore require a
fundamental understanding of the DNA structure–function relationship at interfaces. We …

InterMetalDB: a database and browser of intermolecular metal binding sites in macromolecules with structural information

JB Tran, A Krezel - Journal of Proteome Research, 2021 - ACS Publications
InterMetalDB is a free-of-charge database and browser of intermolecular metal binding sites
that are present on the interfaces of macromolecules forming larger assemblies based on …

Direct experimental evidence for quadruplex–quadruplex interaction within the human ILPR

JD Schonhoft, R Bajracharya, S Dhakal… - Nucleic acids …, 2009 - academic.oup.com
Here we report the analysis of dual G-quadruplexes formed in the four repeats of the
consensus sequence from the insulin-linked polymorphic region (ACAGGGGTGTGGGG; …