Albinism is a pigment disorder affecting eye, skin and/or hair. Patients usually have
decreased melanin in affected tissues and suffer from severe visual abnormalities, including …

Channel proteins are vital for conducting ions throughout the body and are especially
relevant to retina physiology. Inward rectifier potassium (Kir) channels are a class of K+ …

Retinal pigment epithelial (RPE) cells are exclusive to the retina, critically multifunctional in
maintaining the visual functions and health of photoreceptors and the retina. Despite their …

Pathogenic variants in RPE65 lead to retinal diseases, causing a vision impairment. In this
work, we investigated the pathomechanism behind the frequent RPE65 variant, c. 11+ 5G> …

Age-related macular degeneration (AMD) is the most prevalent cause of blindness in the
developed world. Vision loss in the advanced stages of the disease is caused by atrophy of …

Age-related macular degeneration (AMD) is associated with the dysfunction and
degeneration of retinal pigment epithelium (RPE) cells. Here, we examined how the …

Ciliary neurotrophic factor (CNTF) is a pluripotent neurotrophic factor originally isolated from
chicken embryo ciliary neurons. It has a powerful role in developing and maintaining the …

The cotton aphid Aphis gossypii Glover is an important cotton pest, and means of controlling
this insect is a primary research focus. Although biological rhythm is an important …

The retinal pigmented epithelium (RPE) plays a critical role in photoreceptor survival and
function. RPE deficits are implicated in a wide range of diseases that result in vision loss …

Human cytomegalovirus (HCMV) has a broad cellular tropism and epithelial cells are
important physiological targets during infection. The retinal pigment epithelial cell line ARPE …