The Pivotal Role of Nrf2 Signal Axis in Intervertebral Disc Degeneration

C Pan, W Hou, X Deng, J Liu, R Chi… - Journal of …, 2023 - Taylor & Francis
Intervertebral disc degeneration (IDD) is considered as a dominant contributor to low back
pain (LBP), causing severe pain, limited range of lumbar motion, physical dysfunction, and …

Cytokine, chemokine alterations and immune cell infiltration in Radiation-induced lung injury: Implications for prevention and management

H Guo, R Yu, H Zhang, W Wang - International Immunopharmacology, 2024 - Elsevier
Radiation therapy is one of the primary treatments for thoracic malignancies, with radiation-
induced lung injury (RILI) emerging as its most prevalent complication. RILI encompasses …

The Mitochondrial-Derived Peptide MOTS-c Alleviates Radiation Pneumonitis via an Nrf2-Dependent Mechanism

Y Zhang, J Huang, Y Zhang, F Jiang, S Li, S He, J Sun… - Antioxidants, 2024 - mdpi.com
Radiation pneumonitis (RP) is a prevalent and fatal complication of thoracic radiotherapy
due to the lack of effective treatment options. RP primarily arises from mitochondrial injury in …

[HTML][HTML] Prevention and treatment of radiation injury by traditional Chinese medicine: A review

L He, S Edi, J Ma, Z Kong, C Dai, L Huang… - Chinese Herbal …, 2024 - Elsevier
Nuclear radiation exposure events and tumor radiotherapy are highly susceptible to a range
of psychological, physiological and other health problems, which can seriously affect …

[HTML][HTML] Anisodamine ameliorates crystalline silica-exposed pulmonary inflammation and fibrosis via the α7nAChR/JAK2/STAT3 signaling pathway

M Liu, H Liu, H Kang, J Wu, P Xing, X Ding… - Ecotoxicology and …, 2025 - Elsevier
Silicosis is a systemic disease marked by diffuse pulmonary fibrosis resulting from
prolonged inhalation of crystalline silica (CS) dust. This study aimed to examine the effects …

Protective effects of herbal compounds against cyclophosphamide-induced organ toxicity: a pathway-centered approach

P Srirangan, EP Sabina - Drug and Chemical Toxicology, 2025 - Taylor & Francis
Cyclophosphamide is a key component of numerous chemotherapeutic protocols,
demonstrating broad-spectrum efficacy against various malignancies and non-cancerous …

Formulations of traditional Chinese medicine for the prevention and treatment of radiation-induced injury

H Niu, Z Tang, Q Chi, L Du, Y Jin - Acupuncture and Herbal …, 2024 - journals.lww.com
The likelihood of radiation-induced injury (RII) has increased. Currently, the chemical drugs
used to prevent and control radiation damage have some drawbacks, such as high toxicity …

A Review on the Chemical Properties, Plant Sources, Anti‐shock Effects, Pharmacokinetics, Toxicity, and Clinical Applications of Anisodamine

Q Xia, R Pingcuo, C Yang, W Xiong… - Chemistry & …, 2024 - Wiley Online Library
Alkaloids are natural products that occur widely in many herbal plants. Anisodamine, widely
present in the Solanaceae family, is an alkaloid extracted from the roots of the Anisodus …

[HTML][HTML] 基于非靶向代谢组学探索辐射诱导的小鼠肺上皮细胞代谢改变

FAN Hao, GE Xiangwei, Z Xin, LI Yao… - Chinese Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
背景与目的代谢变化是放射性肺炎的重要特征之一. 放疗作为胸部肿瘤治疗的常规手段,
在有效杀伤肿瘤细胞的同时也会引发局部炎症和纤维化等不良反应, 进而导致治疗效果受限 …

[PDF][PDF] 基于非靶向代谢组学探索辐射诱导的小鼠肺上皮细胞代谢改变

范昊, 葛祥伟, 周鑫, 李瑶, 刘巧维, 胡毅 - pdfs.semanticscholar.org
背景与目的代谢变化是放射性肺炎的重要特征之一. 放疗作为胸部肿瘤治疗的常规手段,
在有效杀伤肿瘤细胞的同时也会引发局部炎症和纤维化等不良反应, 进而导致治疗效果受限 …