Uncovering the multifaceted roles played by neutrophils in allogeneic hematopoietic stem cell transplantation

C Tecchio, MA Cassatella - Cellular & molecular immunology, 2021 - nature.com
Allogeneic hematopoietic stem cell transplantation (alloHSCT) is a life-saving procedure
used for the treatment of selected hematological malignancies, inborn errors of metabolism …

Advances and challenges in cytomegalovirus detection methods for liver transplant donors

X Li, Y Zhong, Y Qiao, H Li, X Hu, S Imani, S Zheng… - Diagnostics, 2023 - mdpi.com
Cytomegalovirus (CMV) infection is a highly prevalent opportunistic infection among liver
transplant recipients. When the liver donor is infected with CMV, there is a risk of …

Cytomegalovirus durably primes neutrophil oxidative burst

TF Marandu, M Dombek, M Gutknecht… - Journal of Leukocyte …, 2023 - academic.oup.com
Cytomegalovirus (CMV) is a ubiquitous herpes virus that infects most humans, thereafter
persisting lifelong in tissues of the host. It is a known pathogen in immunosuppressed …

In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome

H Taher, E Mahyari, C Kreklywich, LS Uebelhoer… - PLoS …, 2020 - journals.plos.org
Cytomegaloviruses (CMVs) are highly adapted to their host species resulting in strict
species specificity. Hence, in vivo examination of all aspects of CMV biology employs animal …

The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal β-hairpin and induces neutrophil migration as a selective …

C Berg, MJ Wedemeyer, M Melynis… - PLoS …, 2022 - journals.plos.org
Human cytomegalovirus (HCMV) is a major pathogen in immunocompromised patients. The
UL146 gene exists as 14 diverse genotypes among clinical isolates, which encode 14 …

Neutrophils enhance the clearance of systemic amyloid deposits in a murine amyloidoma model

TJ Hancock, M Vlasyuk, JS Foster, S Macy… - Frontiers in …, 2024 - frontiersin.org
Introduction Amyloid-specific antibodies have been shown to opsonize and enhance
amyloid clearance in systemic amyloidosis mouse models. However, the immunological …

Mouse cytomegalovirus differentially exploits cell surface glycosaminoglycans in a cell type-dependent and MCK-2-independent manner

SM Pontejo, PM Murphy - Viruses, 2019 - mdpi.com
Many viruses initiate interaction with target cells by binding to cell surface
glycosaminoglycans (GAGs). Heparan sulfate (HS) appears to be particularly important in …

Treatment of glioblastoma with current oHSV variants reveals differences in efficacy and immune cell recruitment

JW Jackson, BL Hall, M Marzulli, VK Shah… - Molecular Therapy …, 2021 - cell.com
Oncolytic herpes simplex viruses (oHSVs) have demonstrated efficient lytic replication in
human glioblastoma tumors using immunodeficient mouse models, but early-phase clinical …