Prospects and challenges for cell-cultured fat as a novel food ingredient

KD Fish, NR Rubio, AJ Stout, JSK Yuen… - Trends in food science & …, 2020 - Elsevier
Background In vitro meat production has been proposed as a solution to environmental and
animal welfare issues associated with animal agriculture. While most academic work on cell …

Brown and beige fat: from molecules to physiology and pathophysiology

S Carobbio, AC Guénantin, I Samuelson… - … et Biophysica Acta (BBA …, 2019 - Elsevier
The adipose organ portrays adipocytes of diverse tones: white, brown and beige, each type
with distinct functions. Adipocytes orchestrate their adaptation and expansion to provide …

EPAC1 enhances brown fat growth and beige adipogenesis

L Reverte-Salisa, S Siddig, S Hildebrand, X Yao… - Nature Cell …, 2024 - nature.com
Brown adipose tissue (BAT) is a central thermogenic organ that enhances energy
expenditure and cardiometabolic health. However, regulators that specifically increase the …

Human beige adipocytes for drug discovery and cell therapy in metabolic diseases

AM Singh, L Zhang, J Avery, A Yin, Y Du… - Nature …, 2020 - nature.com
Human beige adipocytes (BAs) have potential utility for the development of therapeutics to
treat diabetes and obesity-associated diseases. Although several reports have described …

Scalable Generation of Pre‐Vascularized and Functional Human Beige Adipose Organoids

M Escudero, L Vaysse, G Eke, M Peyrou… - Advanced …, 2023 - Wiley Online Library
Obesity and type 2 diabetes are becoming a global sociobiomedical burden. Beige
adipocytes are emerging as key inducible actors and putative relevant therapeutic targets for …

[HTML][HTML] A renewable source of human beige adipocytes for development of therapies to treat metabolic syndrome

S Su, AR Guntur, DC Nguyen, SS Fakory, CC Doucette… - Cell reports, 2018 - cell.com
Molecular-and cellular-based therapies have the potential to reduce obesity-associated
disease. In response to cold, beige adipocytes form in subcutaneous white adipose tissue …

Studying Brown Adipose Tissue in a Human in vitro Context

I Samuelson, A Vidal-Puig - Frontiers in endocrinology, 2020 - frontiersin.org
New treatments for obesity and associated metabolic disease are increasingly warranted
with the growth of the obesity pandemic. Brown adipose tissue (BAT) may represent a …

The mesenchymoangioblast, mesodermal precursor for mesenchymal and endothelial cells

II Slukvin, A Kumar - Cellular and Molecular Life Sciences, 2018 - Springer
Mesenchymoangioblast (MB) is the earliest precursor for endothelial and mesenchymal
cells originating from APLNR+ PDGFRα+ KDR+ mesoderm in human pluripotent stem cell …

Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration

ID Derman, T Rivera, LG Cerda, YP Singh… - … Journal of Extreme …, 2024 - iopscience.iop.org
This comprehensive review explores the multifaceted landscape of skin bioprinting,
revolutionizing dermatological research. The applications of skin bioprinting utilizing …

Biofabrication of vascularized adipose tissues and their biomedical applications

AS Karanfil, F Louis, M Matsusaki - Materials Horizons, 2023 - pubs.rsc.org
Recent advances in adipose tissue engineering and cell biology have led to the
development of innovative therapeutic strategies in regenerative medicine for adipose tissue …