Clear cell renal cell carcinoma (ccRCC) is the most frequent histological kidney cancer
subtype. Over the last decade, significant progress has been made in identifying the genetic …

Airway epithelial barrier dysfunction is frequently observed in asthma and may have
important implications. The physical barrier function of the airway epithelium is tightly …

Epidemiological studies have shown a dramatic increase in the incidence and the
prevalence of allergic diseases over the last several decades. Environmental triggers …

Abstract Rationale and Objective Plasma extracellular vesicles (EVs) represent a vital
source of molecular information about health and disease states. Due to their heterogenous …

During its 30 years history, the Hygiene Hypothesis has shown itself to be adaptable
whenever it has been challenged by new scientific developments and this is a still a …

Chronic obstructive pulmonary disease (COPD), asthma and cystic fibrosis (CF) are distinct
respiratory diseases that share features such as the obstruction of small airways and …

Extracellular vesicles (EVs) are membranous structures, which are secreted by almost every
cell type analyzed so far. In addition to their importance for cell-cell communication under …

Inflammation is a complex physiological phenomenon, which is the body's defensive
response, but abnormal inflammation can have adverse effects, and many diseases are …

Abstract Introduction Pterostilbene (Pts) may be used for allergic asthma treatment. The
AMPK/Sirt1 and Nrf2/HO‐1 pathways are potential targets for asthma treatement. However …

Asthma is a chronic inflammatory disease of the respiratory tract characterized by recurrent
breathing problems resulting from airway obstruction and hyperresponsiveness. Human …