Leptin and the brain: influences on brain development, cognitive functioning and psychiatric disorders

OM Farr, MA Tsoukas, CS Mantzoros - Metabolism, 2015 - Elsevier
Receptors of leptin, the prototypical adipokine, are expressed throughout the cortex and
several other areas of the brain. Although typically studied for its role in energy intake and …

Neuroprotective Potency of Neolignans in Magnolia officinalis Cortex Against Brain Disorders

S Zhu, F Liu, R Zhang, Z Xiong, Q Zhang… - Frontiers in …, 2022 - frontiersin.org
In recent years, neurological diseases including Alzheimer's disease, Parkinson's disease
and stroke are one of the main causes of death in the world. At the same time, the incidence …

Ameliorative effect of saffron aqueous extract on hyperglycemia, hyperlipidemia, and oxidative stress on diabetic encephalopathy in streptozotocin induced …

S Samarghandian, M Azimi-Nezhad… - BioMed research …, 2014 - Wiley Online Library
Diabetic encephalopathy is one of the severe complications in patients with diabetes
mellitus. Findings indicate that saffron extract has antioxidant properties but its underlying …

Hypoglycemic and antioxidant activities of paeonol and its beneficial effect on diabetic encephalopathy in streptozotocin-induced diabetic rats

J Liu, S Wang, L Feng, D Ma, Q Fu, Y Song… - Journal of Medicinal …, 2013 - liebertpub.com
Diabetic encephalopathy (DE) is one of the severe complications in patients with diabetes
mellitus. Paeonol, an active compound isolated from the root bark of Paeonia suffruticosa …

Neuronal nitric oxide synthase has a role in the detrimental effects of lipopolysaccharide on spatial memory and synaptic plasticity in rats

A Anaeigoudari, M Soukhtanloo, MN Shafei… - Pharmacological …, 2016 - Springer
Background The role of neuronal nitric oxide synthase (nNOS) in lipopolysaccharide (LPS)-
induced memory and synaptic plasticity impairment was investigated. Methods The rats …

[HTML][HTML] Impact of oxidative/nitrosative stress and inflammation on cognitive functions in patients with recurrent depressive disorders

M Talarowska, K Bobińska… - … medical journal of …, 2014 - ncbi.nlm.nih.gov
Data show that up to 38.2% of the European population have a mental disorder and that
recurrent depressive disorder (rDD) is among the most commonly diagnosed disabling …

Increased contextual fear conditioning in iNOS knockout mice: additional evidence for the involvement of nitric oxide in stress-related disorders and contribution of the …

SF Lisboa, FV Gomes, AL Silva… - International Journal …, 2015 - academic.oup.com
Background: Inducible or neuronal nitric oxide synthase gene deletion increases or
decreases anxiety-like behavior in mice, respectively. Since nitric oxide and …

Tuberal hypothalamic neurons secreting the satiety molecule Nesfatin-1 are critically involved in paradoxical (REM) sleep homeostasis

S Jego, D Salvert, L Renouard, M Mori, R Goutagny… - PLoS …, 2012 - journals.plos.org
The recently discovered Nesfatin-1 plays a role in appetite regulation as a satiety factor
through hypothalamic leptin-independent mechanisms. Nesfatin-1 is co-expressed with …

Effect of selenium on fluoride-induced changes in synaptic plasticity in rat hippocampus

W Qian, K Miao, T Li, Z Zhang - Biological trace element research, 2013 - Springer
This study was conducted to further explore the effect of selenium on fluoride-induced
changes in the synaptic plasticity in rat hippocampus. Animals were randomly divided into …

Comparison of spatial learning in the partially baited radial-arm maze task between commonly used rat strains: Wistar, Spargue-Dawley, Long-Evans, and outcrossed …

Ç Gökçek-Saraç, M Wesierska… - Learning & …, 2015 - Springer
Strain-related differences in animals' cognitive ability affect the outcomes of experiments and
may be responsible for discrepant results obtained by different research groups. Therefore …