An injectable liposome-anchored teriparatide incorporated gallic acid-grafted gelatin hydrogel for osteoarthritis treatment
G Li, S Liu, Y Chen, J Zhao, H Xu, J Weng, F Yu… - Nature …, 2023 - nature.com
Intra-articular injection of therapeutics is an effective strategy for treating osteoarthritis (OA),
but it is hindered by rapid drug diffusion, thereby necessitating high-frequency injections …
but it is hindered by rapid drug diffusion, thereby necessitating high-frequency injections …
Cucurbitacin E reduces IL-1β-induced inflammation and cartilage degeneration by inhibiting the PI3K/Akt pathway in osteoarthritic chondrocytes
L Wang, H Xu, X Li, H Chen, H Zhang, X Zhu… - Journal of Translational …, 2023 - Springer
Background Osteoarthritis is a degenerative joint disease. Cartilage degeneration is the
earliest and most important pathological change in osteoarthritis, and persistent …
earliest and most important pathological change in osteoarthritis, and persistent …
Curcumenol regulates Histone H3K27me3 demethylases KDM6B affecting Succinic acid metabolism to alleviate cartilage degeneration in knee osteoarthritis
W Chen, J Xiao, Y Zhou, W Liu, J Jian, J Yang, B Chen… - Phytomedicine, 2024 - Elsevier
Background Cartilage metabolism dysregulation is a crucial driver in knee osteoarthritis
(KOA). Modulating the homeostasis can mitigate the cartilage degeneration in KOA …
(KOA). Modulating the homeostasis can mitigate the cartilage degeneration in KOA …
Lesion-localized hydrogels functionalized with engineered extracellular matrix restore cellular homeostasis by enhancing mitochondrial energy metabolism for …
Q Pang, Z Chen, J Zhan, J Liu, X Li, W Zhao… - Chemical Engineering …, 2024 - Elsevier
Cartilage damage and degeneration are fundamental pathological features of osteoarthritis
(OA), attributed largely to disruptions in chondrocyte homeostasis. Tissue engineering …
(OA), attributed largely to disruptions in chondrocyte homeostasis. Tissue engineering …
Characterization and advancement of an evaluation method for the treatment of spontaneous osteoarthritis in STR/ort mice: GRGDS peptides as a potential treatment …
MF Chen, CC Hu, YH Hsu, YT Chiu, KL Chen… - Biomedicines, 2023 - mdpi.com
STR/ort mice spontaneously exhibit the typical osteoarthritis (OA) phenotype. However,
studies describing the relationship between cartilage histology, epiphyseal trabecular bone …
studies describing the relationship between cartilage histology, epiphyseal trabecular bone …
A lightweight browser-based tool for collaborative and blinded image analysis
P Schippers, G Rösch, R Sohn, M Holzapfel… - Journal of …, 2024 - mdpi.com
Collaborative manual image analysis by multiple experts in different locations is an essential
workflow in biomedical science. However, sharing the images and writing down results by …
workflow in biomedical science. However, sharing the images and writing down results by …
Animal models of osteoarthritis: The benefits and costs of reducing variability
Animal models of osteoarthritis | Bone & Joint header advert Bone and Joint logo Journals &
Services About us About us Information for advertisers Information for librarians Carbon …
Services About us About us Information for advertisers Information for librarians Carbon …
[HTML][HTML] Postnatal deletion of Phlpp1 in chondrocytes delays post-traumatic osteoarthritis in male mice
SR Weaver, KM Arnold, E Peralta-Herrera… - … and Cartilage Open, 2025 - Elsevier
Objective Osteoarthritis is a chronic, debilitating disease that causes long-term pain and
immobility. Germline deletion of Phlpp1 or administration of small molecules that inhibit …
immobility. Germline deletion of Phlpp1 or administration of small molecules that inhibit …
Localized Hydrogel Microspheres for Osteoarthritis Treatment: Recruitment and Differentiation of Stem Cells
Q Pang, Z Chen, J Zhan, J Liu, J Liu, W Zhao… - Advanced Healthcare … - Wiley Online Library
Osteoarthritis (OA) represents a common degenerative joint disorder marked by progressive
cartilage degradation, necessitating innovative therapeutic approaches beyond symptom …
cartilage degradation, necessitating innovative therapeutic approaches beyond symptom …
[PDF][PDF] Characterization and Advancement of an Evaluation Method for the Treatment of Spontaneous Osteoarthritis in STR/ort Mice: GRGDS Peptides as a Potential …
MF Chen, CC Hu, YH Hsu, YT Chiu, KL Chen… - 2023 - academia.edu
STR/ort mice spontaneously exhibit the typical osteoarthritis (OA) phenotype. However,
studies describing the relationship between cartilage histology, epiphyseal trabecular bone …
studies describing the relationship between cartilage histology, epiphyseal trabecular bone …