The role of berberine in Covid-19: potential adjunct therapy
Abstract Coronavirus disease 2019 (Covid-19) is a global diastrophic disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Covid-19 leads to …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Covid-19 leads to …
Targeting cyclin-dependent kinase 1 (CDK1) in cancer: molecular docking and dynamic simulations of potential CDK1 inhibitors
Cell cycle dysregulation is a characteristic hallmark of malignancies, which results in
uncontrolled cell proliferation and eventual tumor formation. Cyclin-dependent kinase 1 …
uncontrolled cell proliferation and eventual tumor formation. Cyclin-dependent kinase 1 …
COVID-19 diagnostic methods in developing countries
COVID-19 has become one of the few leading causes of death and has evolved into a
pandemic that disrupts everyone's routine, and balanced way of life worldwide, and will …
pandemic that disrupts everyone's routine, and balanced way of life worldwide, and will …
Combination of Spirulina platensis, Ganoderma lucidum and Moringa oleifera Improves Cardiac Functions and Reduces Pro-Inflammatory Biomarkers in Preclinical …
V Quagliariello, MG Basilicata, G Pepe… - Journal of …, 2022 - mdpi.com
Anthracyclines are essential adjuvant therapies for a variety of cancers, particularly breast,
gastric and esophageal cancers. Whilst prolonging cancer-related survival, these agents …
gastric and esophageal cancers. Whilst prolonging cancer-related survival, these agents …
An insight into the mixed quantum mechanical-molecular dynamics simulation of a ZnII-Curcumin complex with a chosen DNA sequence that supports experimental …
An important aspect of research pertaining to Curcumin (HCur) is the need to arrest its
degradation in aqueous solution and in biological milieu. This may be achieved through …
degradation in aqueous solution and in biological milieu. This may be achieved through …
Pentafuhalol-B, a Phlorotannin from Brown Algae, Strongly Inhibits the PLK-1 Overexpression in Cancer Cells as Revealed by Computational Analysis
Polo-like kinase-1 (PLK-1) is an essential mitotic serine/threonine (Ser/Thr) kinase that
belongs to the Polo-like kinase (PLK) family and is overexpressed in non-small cell lung …
belongs to the Polo-like kinase (PLK) family and is overexpressed in non-small cell lung …
Mechanistic QSAR analysis to predict the binding affinity of diverse heterocycles as selective cannabinoid 2 receptor inhibitor
RD Jawarkar, MEA Zaki, SA Al-Hussain… - Journal of Taibah …, 2023 - Taylor & Francis
CB2R are fascinating targets for neuropathic pain and mood disorders because of their
improved biological characteristics. Experimental data on 1296 cannabinoid-2 receptor …
improved biological characteristics. Experimental data on 1296 cannabinoid-2 receptor …
The importance of good practices and false hits for QSAR-driven virtual screening real application: a SARS-CoV-2 main protease (Mpro) case study
Computer-Aided Drug Design (CADD) approaches, such as those employing quantitative
structure-activity relationship (QSAR) methods, are known for their ability to uncover novel …
structure-activity relationship (QSAR) methods, are known for their ability to uncover novel …
In-silico studies to recognize repurposing therapeutics toward arginase-I inhibitors as a potential onco-immunomodulators
MEA Zaki, SA Al-Hussain, AA Al-Mutairi… - Frontiers in …, 2023 - frontiersin.org
Rudolf Virchow was the first person to point out the important link between immune function
and cancer. He did this by noticing that leukocytes were often found in tumors …
and cancer. He did this by noticing that leukocytes were often found in tumors …
Utilizing coordination chemistry through formation of a CuII-quinalizarin complex to manipulate cell biology: an in vitro, in silico approach
S Chatterjee, CK Jain, T Saha, S Roychoudhury… - Journal of Inorganic …, 2023 - Elsevier
Quinalizarin, an analogue of anthracycline anticancer agents, is an anticancer agent itself. A
Cu II complex was prepared and characterized by elemental analysis, UV-Vis & IR …
Cu II complex was prepared and characterized by elemental analysis, UV-Vis & IR …