One immune system plays many parts: The dynamic role of the immune system in chronic pain and opioid pharmacology

S Mustafa, JE Bajic, B Barry, S Evans, KR Siemens… - …, 2023 - Elsevier
The transition from acute to chronic pain is an ongoing major problem for individuals, society
and healthcare systems around the world. It is clear chronic pain is a complex …

Emodin alleviates arthritis pain through reducing spinal inflammation and oxidative stress

DW Cheng, YF Yue, CX Chen, YD Hu… - Molecular …, 2022 - journals.sagepub.com
Chronic pain is the predominant problem for rheumatoid arthritis patients, and negatively
affects quality of life. Arthritis pain management remains largely inadequate, and developing …

Effectiveness of non-pharmacological therapies for chronic pain in people with autoimmune diseases in Africa: A protocol for a systematic review and meta-analysis

GG Gebremeskel, TG Haile, GT Gebrewahd, A Hailay… - PloS one, 2024 - journals.plos.org
Background Autoimmune diseases affect 5–10% of the global population and cause chronic
pain and impaired functionality. Chronic pain management involves pharmacological and …

Neuronal CRMP2 phosphorylation inhibition by the flavonoid, naringenin, contributes to the reversal of spinal sensitization and arthritic pain improvement

YP Jiang, S Wang, WD Lai, XQ Wu, Y Jin, ZH Xu… - Arthritis Research & …, 2022 - Springer
Background Rheumatoid arthritis patients usually suffer from arthritic chronic pain. However,
due to an incomplete understanding of the mechanisms underlying autoimmune disorders …

A multicenter study to evaluate pain characteristics in osteogenesis imperfecta

M Rodriguez Celin, KM Kruger… - American Journal of …, 2023 - Wiley Online Library
The objective was to describe pain characteristics and treatments used in individuals with
varying severity of osteogenesis imperfecta (OI) and investigate pain‐associated variables …

[HTML][HTML] Hyperactive lateral habenula mediates the comorbidity between rheumatoid arthritis and depression-like behaviors

P Wu, W Li, R Lv, X Cheng, F Lian, W Cai, Y Hu… - Brain, Behavior, and …, 2024 - Elsevier
Rheumatoid arthritis (RA) patients have a high prevalence for depression. On the other
hand, comorbid with depression is associated with worse prognosis for RA. However, little is …

Prevalence, characteristics, and health burden of rheumatoid arthritis in the US veteran population

JL Morse, N Afari, SB Norman, M Guma… - Journal of Psychiatric …, 2023 - Elsevier
Objective To examine the prevalence, characteristics, and physical and mental health
burden of rheumatoid arthritis (RA) in a nationally representative sample of US military …

Is erectile dysfunction associated with osteoarthritis and rheumatoid arthritis? Insights from a population-based study

Y Yan, L Zhou, R La, W Xu, L Li, D Jiang… - Sexual …, 2024 - academic.oup.com
Background The correlation between osteoarthritis (OA) and rheumatoid arthritis (RA), both
significant components of arthritis, and erectile dysfunction (ED) has yet to be thoroughly …

Wangbi granule as a combination therapy to achieve clinical deep remission in rheumatoid arthritis: protocol for a multicenter, triple-blind, randomised, placebo …

J Wang, Z Wang, T Lan, L Zhang, Z Li, X Wang, Q Zou… - Chinese Medicine, 2023 - Springer
Introduction Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that
may lead to bone erosion and disability. Although there are many biological therapies in RA …

The mediting role of psychological resilience on the negative effect of pain in patients with rheumatoid arthritis: A cross-sectional study

S Xu, Q Zhang, J Zhou - Plos one, 2023 - journals.plos.org
The objective of this study was to investigate the direct effects of pain-induced depression
and anxiety, as well as the mediating role of psychological resilience, on the psychological …