The sirtuin family in health and disease

QJ Wu, TN Zhang, HH Chen, XF Yu, JL Lv… - … and Targeted Therapy, 2022 - nature.com
Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

[HTML][HTML] Oxidative stress and diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications

Q Kang, C Yang - Redox biology, 2020 - Elsevier
Oxidative stress, a cytopathic outcome of excessive generation of ROS and the repression of
antioxidant defense system for ROS elimination, is involved in the pathogenesis of multiple …

[HTML][HTML] Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

T Zhao, W Wu, L Sui, Q Huang, Y Nan, J Liu, K Ai - Bioactive Materials, 2022 - Elsevier
Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …

New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury

J Wang, S Toan, H Zhou - Angiogenesis, 2020 - Springer
As reperfusion therapies have become more widely used in acute myocardial infarction
patients, ischemia-induced myocardial damage has been markedly reduced, but reperfusion …

Chlorpyrifos-mediated mitochondrial calcium overload induces EPC cell apoptosis via ROS/AMPK/ULK1

Z Miao, Z Miao, S Feng, S Xu - Fish & shellfish immunology, 2023 - Elsevier
Chlorpyrifos (CPF) is a typical organophosphate insecticide known to has serious
toxicological effects on aquatic animals and causes many environmental contamination …

The cardioprotective effects of the new crystal form of puerarin in isoproterenol-induced myocardial ischemia rats based on metabolomics

Y Zhou, M Li, J Song, Y Shi, X Qin, Z Gao, Y Lv, G Du - Scientific reports, 2020 - nature.com
Puerarin has shown unique pharmacological effects on myocardial ischemia (MI). Changing
the crystal form is an effective approach to improve the cardioprotective effects of puerarin …

Phenylpropanoids and its derivatives: biological activities and its role in food, pharmaceutical and cosmetic industries

Neelam, A Khatkar, KK Sharma - Critical Reviews in Food Science …, 2020 - Taylor & Francis
Phenylpropanoids and their derivatives are plant secondary metabolites widely present in
fruits, vegetables, cereal grains, beverages, spices and herbs. They are known to have …

Potential implications of polyphenols on aging considering oxidative stress, inflammation, autophagy, and gut microbiota

M Wu, Q Luo, R Nie, X Yang, Z Tang… - Critical reviews in food …, 2021 - Taylor & Francis
Naturally occurring compounds polyphenols are secondary metabolites of plants, comprised
several categories, namely, flavonoids, phenolic acids, lignans and stilbenes. The biological …

Cardiovascular effects of caffeic acid and its derivatives: a comprehensive review

H Silva, NMF Lopes - Frontiers in physiology, 2020 - frontiersin.org
Caffeic acid (CA) and its phenethyl ester (CAPE) are naturally occurring hydroxycinnamic
acids with an interesting array of biological activities; eg, antioxidant, anti-inflammatory …

Resveratrol, novel application by preconditioning to attenuate myocardial ischemia/reperfusion injury in mice through regulate AMPK pathway and autophagy level

H Li, F Zheng, Y Zhang, J Sun, F Gao… - Journal of Cellular and …, 2022 - Wiley Online Library
Myocardial ischemia/reperfusion injury (MI/RI) is the main cause of deaths in the worldwide,
leading to severe cardiac dysfunction. Resveratrol (RSV) is a polyphenol plant‐derived …