Successful treatment of tuberculosis (TB) can be hampered by Mycobacterium tuberculosis
populations that are temporarily able to survive antibiotic pressure in the absence of drug …

The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …

Abstract Treatment of tuberculosis (TB) has been a therapeutic challenge because of not
only the naturally high resistance level of Mycobacterium tuberculosis to antibiotics but also …

Tuberculosis (TB) has become a curable disease, thanks to the discovery of antibiotics.
However, it has remained one of the most difficult infections to treat. Most current TB …

Mycobacterium tuberculosis enters the host by inhalation of an infectious aerosol and
replicates in the alveolar macrophages until the host's immune defense causes …

Tuberculosis exerts a tremendous burden on global health, with∼ 9 million new infections
and∼ 2 million deaths annually. The Mycobacterium tuberculosis complex (MTC) was …

Tuberculosis (TB) is an infectious disease that poses a serious threat to human health.
Rifampin (RIF) is an important first-line anti-TB drug, and rifampin resistance (RIF-R) is a key …

Mycobacterium tuberculosis (M. tb) has a complex lifestyle in different environments and
involving several developmental stages. The success of M. tb results from its remarkable …

Tuberculosis is one of the deadliest infectious diseases existing in the world since ancient
times and still possesses serious threat across the globe. Each year the number of cases …

During lung infection, Mycobacterium tuberculosis resides in macrophages and subverts the
bactericidal mechanisms of these professional phagocytes. Comprehension of this host …