Modern genetic approaches are powerful in providing access to diverse cell types in the
brain and facilitating the study of their function. Here, we report a large set of driver and …

Uncovering the wiring rules employed by neurons during development represents a
formidable challenge with important repercussions for neurodevelopmental disorders …

INTRODUCTION The establishment of neuronal circuits in the cerebral cortex of mammals is
an important developmental process extending over embryonic and postnatal periods, from …

Microglia have emerged as critical regulators of synapse development and circuit formation
in the healthy brain. To date, examination of microglia in such processes has largely been …

The activity-dependent rules that govern the wiring of GABAergic interneurons are not well
understood. Chandelier cells (ChCs) are a type of GABAergic interneuron that control …

One of the most intriguing features of inhibitory synapses is the precision by which they
innervate their target, not only at the cellular level but also at the subcellular level (ie axo …

Among the diverse interneuron subtypes in the neocortex, chandelier cells (ChCs) are the
only population that selectively innervate pyramidal neurons (PyNs) at their axon initial …

Neurons form stereotyped microcircuits that underlie specific functions. In the vertebrate
retina, the primary rod and cone pathways that convey dim and bright light signals …

The most prominent structural hallmark of the mammalian neocortical circuitry is the layer-
based organization of specific cell types and synaptic inputs. Accordingly, cortical inhibitory …

Interregional neuronal communication is pivotal to instructing and adjusting cortical circuit
assembly. Subcortical neuromodulatory systems project long-range axons to the cortex and …