Platelets: the emerging clinical diagnostics and therapy selection of cancer liquid biopsies
Y Meng, J Sun, Y Zheng, G Zhang, T Yu… - OncoTargets and …, 2021 - Taylor & Francis
Due to the inherent molecular heterogeneity of metastatic tumours and the dynamic
evolution ability of tumour genomes, tumour tissues obtained through biopsy and other …
evolution ability of tumour genomes, tumour tissues obtained through biopsy and other …
The role of miRNAs in regulation of platelet activity and related diseases-a bioinformatic analysis
Z Wicik, P Czajka, C Eyileten, A Fitas, M Wolska… - Platelets, 2022 - Taylor & Francis
MicroRNAs (miRNAs) are small, non-coding RNAs, able to regulate cellular functions by
induction of mRNA degradation and post-transcriptional repression of gene expression …
induction of mRNA degradation and post-transcriptional repression of gene expression …
[HTML][HTML] Real-world outcomes of chemo-antiangiogenesis versus chemo-immunotherapy combinations in EGFR-mutant advanced non-small cell lung cancer patients …
Background Despite the potent efficacy of epidermal growth factor receptor (EGFR)-tyrosine
kinase inhibitors (TKIs) in the treatment of EGFR-mutant non-small cell lung cancer (NSCLC) …
kinase inhibitors (TKIs) in the treatment of EGFR-mutant non-small cell lung cancer (NSCLC) …
[HTML][HTML] High levels of PD-L1 on platelets of NSCLC patients contributes to the pharmacological activity of Atezolizumab
C Colarusso, A Falanga, M Terlizzi, I De Rosa… - Biomedicine & …, 2023 - Elsevier
Several studies have associated platelets (PLTs) to NSCLC prognosis. To understand the
role of PLTs in immunotherapy-treated patients, we used blood samples of NSCLC patients …
role of PLTs in immunotherapy-treated patients, we used blood samples of NSCLC patients …
Machine learning-based analysis of cancer cell-derived vesicular proteins revealed significant tumor-specificity and predictive potential of extracellular vesicles for cell …
M Bukva, G Dobra, E Gyukity-Sebestyen… - Cell Communication and …, 2023 - Springer
Background Although interest in the role of extracellular vesicles (EV) in oncology is
growing, not all potential aspects have been investigated. In this meta-analysis, data …
growing, not all potential aspects have been investigated. In this meta-analysis, data …
Prognostic heterogeneity of Ki67 in non‐small cell lung cancer: A comprehensive reappraisal on immunohistochemistry and transcriptional data
Y Yang, X Shao, Z Li, L Zhang, B Yang… - Journal of Cellular …, 2024 - Wiley Online Library
In the present study, the debatable prognostic value of Ki67 in patients with non‐small cell
lung cancer (NSCLC) was attributed to the heterogeneity between lung adenocarcinoma …
lung cancer (NSCLC) was attributed to the heterogeneity between lung adenocarcinoma …
Full spectrum flow cytometry-powered comprehensive analysis of PBMC as biomarkers for immunotherapy in NSCLC with EGFR-TKI resistance
J Zhou, X Chu, J Zhao, M Xie, J Wu, X Yu… - Biological Procedures …, 2023 - Springer
Background Clinical studies suggest that immune checkpoint inhibitor (ICI) monotherapy
has limited benefits in non-small cell lung cancer (NSCLC) patients after epidermal growth …
has limited benefits in non-small cell lung cancer (NSCLC) patients after epidermal growth …
Predicting the prognosis of operable gastric cancer patients by dynamic changes in platelets before and after surgery: a retrospective cohort study
J Li, X Yang, X Wang, Y Jiang, Z Wang, X Shen… - Journal of Cancer …, 2023 - Springer
Purpose Since the relationship between postoperative platelet count and prognosis is still
unclear, we designed a standardized index of platelet count to predict the prognosis of …
unclear, we designed a standardized index of platelet count to predict the prognosis of …
Development and validation of postoperative and preoperative platelets ratio (PPR) to predict the prognosis of patients undergoing surgery for colorectal cancer: A …
W Yang, X Zheng, M Wu, F Zhang, S Xu… - Cancer …, 2023 - Wiley Online Library
Background Platelets occupy a prominent place in tumor proliferation and metastasis, and
platelet count is relevant to the prognosis of tumor patients. But preoperative platelet counts …
platelet count is relevant to the prognosis of tumor patients. But preoperative platelet counts …
[HTML][HTML] Development and validation of a deep learning-based model to predict response and survival of T790M mutant non-small cell lung cancer patients in early …
N Lou, X Cui, X Lin, R Gao, C Xu, N Qiao… - Translational Lung …, 2024 - ncbi.nlm.nih.gov
Background Epidermal growth factor receptor (EGFR) T790M mutation is the standard
predictive biomarker for third-generation epidermal growth factor receptor tyrosine kinase …
predictive biomarker for third-generation epidermal growth factor receptor tyrosine kinase …