Adaptive optics for optical microscopy

Q Zhang, Q Hu, C Berlage, P Kner… - Biomedical Optics …, 2023 - opg.optica.org
Optical microscopy is widely used to visualize fine structures. When applied to bioimaging,
its performance is often degraded by sample-induced aberrations. In recent years, adaptive …

Multicolor single-molecule localization microscopy: review and prospect

X Chen, X Wang, F Huang, D Ma - PhotoniX, 2024 - Springer
Single-molecule localization microscopy (SMLM) surpasses the diffraction limit by randomly
switching fluorophores between fluorescent and dark states, precisely pinpointing the …

Continuous optical zoom microscope with extended depth of field and 3D reconstruction

C Liu, Z Jiang, X Wang, Y Zheng, YW Zheng, QH Wang - PhotoniX, 2022 - Springer
Microscope such as fluorescence microscope, confocal microscope and two-photon
microscope plays an important role in life science, laser processing and other fields …

Multi-focus light-field microscopy for high-speed large-volume imaging

Y Zhang, Y Wang, M Wang, Y Guo, X Li, Y Chen, Z Lu… - PhotoniX, 2022 - Springer
High-speed visualization of three-dimensional (3D) processes across a large field of view
with cellular resolution is essential for understanding living systems. Light-field microscopy …

Three-dimensional dipole orientation mapping with high temporal-spatial resolution using polarization modulation

S Zhong, L Qiao, X Ge, X Xu, Y Fu, S Gao, K Zhanghao… - PhotoniX, 2024 - Springer
Fluorescence polarization microscopy is widely used in biology for molecular orientation
properties. However, due to the limited temporal resolution of single-molecule orientation …

Deep tissue super-resolution imaging with adaptive optical two-photon multifocal structured illumination microscopy

C Zhang, B Yu, F Lin, S Samanta, H Yu, W Zhang… - PhotoniX, 2023 - Springer
Visualization of axons and dendritic spines is crucial in neuroscience research. However,
traditional microscopy is limited by diffraction-limited resolution and shallow imaging depth …

Self-supervised denoising for multimodal structured illumination microscopy enables long-term super-resolution live-cell imaging

X Chen, C Qiao, T Jiang, J Liu, Q Meng, Y Zeng… - PhotoniX, 2024 - Springer
Detection noise significantly degrades the quality of structured illumination microscopy (SIM)
images, especially under low-light conditions. Although supervised learning based …

Supercontinuum-tailoring multicolor imaging reveals spatiotemporal dynamics of heterogeneous tumor evolution

X Gao, X Huang, Z Chen, L Yang, Y Zhou… - Nature …, 2024 - nature.com
Tumor heterogeneity and tumor evolution contribute to cancer treatment failure. To
understand how selective pressures drive heterogeneous tumor evolution, it would be useful …

Simultaneous multi-plane imaging light-sheet fluorescence microscopy for simultaneously acquiring neuronal activity at varying depths

Z Jiao, Z Zhou, Z Chen, J Xie, Y Mu, J Du, L Fu - Optica, 2023 - opg.optica.org
Acquiring the firing sequence of neurons located in varying depths with cellular resolution is
essential to understand the underlying functional neural circuits of living animals. Light …

Tunable optofluidic Fresnel lens with ring-shaped electrodes

YR Zhao, JB Xu, RY Yuan, X Wang, L Li, C Liu… - Optics and Lasers in …, 2024 - Elsevier
Traditional Fresnel lenses can achieve volume diminution by reducing lens material cost,
thereby achieving further integration in optical systems. However, the solid Fresnel lenses in …