Abstract Purpose of Review In this review, we describe molecular pathological epidemiology
(MPE) studies from around the world that have studied diet and/or lifestyle factors in relation …

Molecular pathological epidemiology (MPE) is an integrative field that utilizes molecular
pathology to incorporate interpersonal heterogeneity of a disease process into …

Background & Aims Serrated polyps (SPs) and conventional adenomas are precursor
lesions for colorectal cancer (CRC), but they are believed to arise via distinct pathways. We …

Molecular pathology diagnostics to subclassify diseases based on pathogenesis are
increasingly common in clinical translational medicine. Molecular pathological epidemiology …

The precision medicine concept and the unique disease principle imply that each patient
has unique pathogenic processes resulting from heterogeneous cellular genetic and …

Exercise and physical activity have been shown to be strongly associated with a decreased
incidence rate of various chronic diseases especially numerous human malignancies. A …

Accumulating evidence indicates that gut microbiota dysbiosis contributes to colorectal
cancer and adenoma. However, a few studies revealed the altered gut mycobiota …

The role of insulin-like growth factor binding protein 2 (IGFBP2) in cancer is unclear. In
general, IGFBP2 is considered to be oncogenic and its expression is often observed to be …

Early‐life (childhood to adolescence) energy balance‐related factors (height, energy
restriction, BMI) have been associated with adult colorectal cancer (CRC) risk. Warburg …

A number of epidemiologic studies have described what appear to be paradoxical
associations, where an incongruous relationship is observed between a certain well …