Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

Apoptosis is a programmed, physiological mode of cell death that plays an important role in
tissue homeostasis. Understanding of the basic mechanisms that underlie apoptosis will …

Histone H2AX is a ubiquitous member of the H2A histone family that differs from the other
H2A histones by the presence of an evolutionarily conserved C-terminal motif …

Chimeric antigen receptor (CAR) T-cell therapy is a promising and rapidly expanding
therapeutic option for a wide range of human malignancies. Despite the ongoing progress of …

Phosphatidylserine (PS), ordinarily sequestered in the plasma membrane inner leaflet,
appears in the outer leaflet during apoptosis, where it triggers non-inflammatory phagocytic …

Human neutrophils constitutively undergo apoptosis and this process is critical for the
resolution of inflammation. Whilst neutrophil apoptosis can be modulated by a wide variety …

During early placentation the trophoblast of the human placenta differentiates to the villous
and extravillous types of trophoblast. Villous trophoblast provides the epithelial cover of the …

Cryopreservation induces many changes in sperm cells, including membrane disorders and
cell death. We tested the hypothesis that apoptosis, a form of programmed cell death, can …

Thromboembolic phenomena have been described in patients with thalassaemia intermedia
and major, although there are relatively few epidemiological data on the overall frequency of …

Villous trophoblast is the epithelial cover of the placental villous tree and comes in direct
contact with maternal blood. The turnover of villous trophoblast includes proliferation and …