Microfluidics for neuronal cell and circuit engineering

R Habibey, JE Rojo Arias, J Striebel… - Chemical …, 2022 - ACS Publications
The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …

Annual Research Review: Early intervention viewed through the lens of developmental neuroscience

CA Nelson, E Sullivan… - Journal of Child …, 2024 - Wiley Online Library
The overarching goal of this paper is to examine the efficacy of early intervention when
viewed through the lens of developmental neuroscience. We begin by briefly summarizing …

Early life adversity shapes social subordination and cell type–specific transcriptomic patterning in the ventral hippocampus

A Kos, JP Lopez, J Bordes, C De Donno, J Dine… - Science …, 2023 - science.org
Adverse events in early life can modulate the response to additional stressors later in life
and increase the risk of developing psychiatric disorders. The underlying molecular …

Beyond cholinesterase inhibition: developmental neurotoxicity of organophosphate ester flame retardants and plasticizers

HB Patisaul, M Behl, LS Birnbaum… - Environmental …, 2021 - ehp.niehs.nih.gov
Background: To date, the toxicity of organophosphate esters has primarily been studied
regarding their use as pesticides and their effects on the neurotransmitter …

[HTML][HTML] Reconceptualizing complex posttraumatic stress disorder: a predictive processing framework for mechanisms and intervention

A Putica, J Agathos - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
In this manuscript, we introduce a framework for interpreting Complex Posttraumatic Stress
Disorder (C-PTSD) through predictive processing, a neuroscience concept explaining the …

Sensitive periods for social development: Interactions between predisposed and learned mechanisms

O Rosa-Salva, U Mayer, E Versace, M Hébert… - Cognition, 2021 - Elsevier
We analysed research that makes use of precocial species as animal models to describe the
interaction of predisposed mechanisms and environmental factors in early learning, in …

Brain plasticity in humans and model systems: advances, challenges, and future directions

L Bonfanti, CJ Charvet - International journal of molecular sciences, 2021 - mdpi.com
Plasticity, and in particular, neurogenesis, is a promising target to treat and prevent a wide
variety of diseases (eg, epilepsy, stroke, dementia). There are different types of plasticity …

The self-regulatory affective touch: a speculative framework for the development of executive functioning

T Farroni, L Della Longa, I Valori - Current Opinion in Behavioral Sciences, 2022 - Elsevier
Highlights•Early tactile experiences are the most direct experience of contact with the
surrounding physical and social environment.•Affective touch interactions may promote …

Brain stars take the lead during critical periods of early postnatal brain development: relevance of astrocytes in health and mental disorders

E Vivi, B Di Benedetto - Molecular Psychiatry, 2024 - nature.com
In the brain, astrocytes regulate shape and functions of the synaptic and vascular
compartments through a variety of released factors and membrane-bound proteins. An …

Acan downregulation in parvalbumin GABAergic cells reduces spontaneous recovery of fear memories

M Lavertu-Jolin, B Chattopadhyaya, P Chehrazi… - Molecular …, 2023 - nature.com
While persistence of fear memories is essential for survival, a failure to inhibit fear in
response to harmless stimuli is a feature of anxiety disorders. Extinction training only …