Infection by protozoan parasites of the genus Leishmania results in the development of
leishmaniasis, an increasingly prevalent group of diseases affecting over 12 million people …

Leishmaniasis is a group of disease caused by the intracellular protozoan parasite of the
genus Leishmania. Infection by different species of Leishmania results in various host …

Diseases caused by Leishmania present a worldwide problem, and current therapeutic
approaches are unable to achieve a sterile cure. Leishmania is able to persist in host cells …

Protozoa of the genus Leishmania cause a wide variety of pathologies ranging from self‐
healing skin lesions to visceral damage, depending on the parasite species. The outcome of …

Toll-like receptors (TLRs) are germline-encoded, non-clonal innate immune receptors,
which are often the first receptors to recognize the molecular patterns on pathogens …

Molecular therapy refers to targeted therapies based on molecules which have been
intelligently directed towards specific biomolecular structures and include small molecule …

Most of the existing Leishmania-related research about TLR-2 agonists was focusing on
their role as adjuvants in the vaccine, few studied its therapeutic effect. This paper aims to …

Leishmaniasis is caused by protozoan parasites of the genus Leishmania and causes a
wide spectrum of clinical manifestations ranging from self-healing cutaneous lesions to the …

The major issues in available therapeutic modalities against leishmaniasis are cost, toxicity,
and the emergence of drug resistance. The aim of this work was to develop a successful …

Abstract Toll‐like receptors (TLRs), members of pattern recognition receptors, are expressed
on many cells of the innate immune system, and their engagements with antigens regulate …