A brief overview of global trends in MSC-based cell therapy

D Jovic, Y Yu, D Wang, K Wang, H Li, F Xu… - Stem cell reviews and …, 2022 - Springer
Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …

How the mechanical microenvironment of stem cell growth affects their differentiation: A review

X Zhang, S Zhang, T Wang - Stem cell research & therapy, 2022 - Springer
Stem cell differentiation is of great interest in medical research; however, specifically and
effectively regulating stem cell differentiation is still a challenge. In addition to chemical …

[HTML][HTML] Stimulating factors for regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells

JQ Zhou, HY Wan, ZX Wang, N Jiang - World Journal of Stem Cells, 2023 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs), distributed in many tissues in the human body, are
multipotent cells capable of differentiating in specific directions. It is usually considered that …

Effect of Hydrogel Matrix and Fluid Shear Stress on the Behavioral Regulation of Mesenchymal Stem Cells

S Kang, X Wu, H Qi, K Yang, R Feng, W Guo… - Small …, 2024 - Wiley Online Library
Development of a micromodel that recapitulates multiple mechanical properties to mimic the
complex mechanical microenvironment is crucial for cell‐based research. Herein, a …

Biomaterials combined with ADSCs for bone tissue engineering: current advances and applications

Y Song, N Wang, H Shi, D Zhang… - Regenerative …, 2023 - academic.oup.com
In recent decades, bone tissue engineering, which is supported by scaffold, seed cells and
bioactive molecules (BMs), has provided new hope and direction for treating bone defects …

Translating material science into bone regenerative medicine applications: state-of-the art methods and protocols

L Di Pietro, V Palmieri, M Papi, W Lattanzi - International Journal of …, 2022 - mdpi.com
In the last 20 years, bone regenerative research has experienced exponential growth thanks
to the discovery of new nanomaterials and improved manufacturing technologies that have …

[HTML][HTML] MiR-20a: a mechanosensitive microRNA that regulates fluid shear stress-mediated osteogenic differentiation via the BMP2 signaling pathway by targeting …

Z Peng, Z Mai, F Xiao, G Liu, Y Wang… - Annals of Translational …, 2022 - ncbi.nlm.nih.gov
Background MicroRNAs (miRNAs) are crucial regulators of diverse biological and
pathological processes. This study aimed to investigate the role of microRNA 20a (miR-20a) …

Viscous microcapsules as microbioreactors to study mesenchymal stem/stromal cells osteolineage commitment

M Ghasemzadeh‐Hasankolaei, JM Miranda… - Small …, 2023 - Wiley Online Library
It is essential to design a multifunctional well‐controlled platform to transfer mechanical cues
to the cells in different magnitudes. This study introduces a platform, a miniaturized …

[HTML][HTML] Strengthening regulations, recent advances and remaining barriers in stem cell clinical translation in China: 2015–2021 in review

C Li - Pharmacological Research, 2022 - Elsevier
A new regulatory regime is being implemented under strict scrutiny for translation of stem
cell medical practices since 2015 in China. The new mode of governance is strengthening to …

Role of Adipose-Derived Mesenchymal Stem Cells in Bone Regeneration

CS Lau, SY Park, LP Ethiraj, P Singh, G Raj… - International Journal of …, 2024 - mdpi.com
Bone regeneration involves multiple factors such as tissue interactions, an inflammatory
response, and vessel formation. In the event of diseases, old age, lifestyle, or trauma, bone …