Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration

JM Sonner, JF Antognini, RC Dutton… - Anesthesia & …, 2003 - journals.lww.com
Studies using molecular modeling, genetic engineering, neurophysiology/pharmacology,
and whole animals have advanced our understanding of where and how inhaled …

Neurochemical mechanisms of the defensive behavior in the dorsal midbrain

ML Brandão, VZ Anseloni, JE Pandossio… - Neuroscience & …, 1999 - Elsevier
Some regions in the mesencephalon, such as dorsal periaqueductal gray, inferior colliculus
and deep layers of superior colliculus have been grouped together as a continuos strip of …

The effects of amphetamine and methamphetamine on the release of norepinephrine, dopamine and acetylcholine from the brainstem reticular formation

M Ferrucci, F Limanaqi, L Ryskalin, F Biagioni… - Frontiers in …, 2019 - frontiersin.org
Amphetamine (AMPH) and methamphetamine (METH) are widely abused psychostimulants,
which produce a variety of psychomotor, autonomic and neurotoxic effects. The behavioral …

Descending inhibitory systems

A Pertovaara, A Almeida - Handbook of clinical neurology, 2006 - Elsevier
Publisher Summary This chapter reviews that the magnitude of the ascending nociceptive
signal and the consequent pain sensation can be greatly influenced by descending …

The relevance of neuronal substrates of defense in the midbrain tectum to anxiety and stress: empirical and conceptual considerations

ML Brandão, AC Troncoso, MA de Souza Silva… - European journal of …, 2003 - Elsevier
The medial hypothalamus, amygdala, and dorsal periaqueductal gray constitute the main
neural substrates for the integration of aversive states in the brain. More recently, some …

The anterior cingulate cortex and its interface with the dorsal periaqueductal grey regulating nitric oxide-mediated panic-like behaviour and defensive antinociception

LL Falconi-Sobrinho, T dos Anjos-Garcia, MA Rebelo… - …, 2024 - Elsevier
The anterior cingulate cortex (ACC) Cg1 (24b) area modulates glutamate-mediated
unconditioned fear and antinociception organised by hypothalamus. However, it remains …

Neuroanatomical approaches of the tectum-reticular pathways and immunohistochemical evidence for serotonin-positive perikarya on neuronal substrates of the …

NC Coimbra, R De Oliveira, RL Freitas, SJ Ribeiro… - Experimental …, 2006 - Elsevier
Deep layers of the superior colliculus, the dorsal periaqueductal gray matter and the inferior
colliculus are midbrain structures involved in the generation of defensive behavior and fear …

Defensive and emotional behavior modulation by serotonin in the periaqueductal gray

P Vázquez-León, A Miranda-Páez… - Cellular and Molecular …, 2023 - Springer
Abstract Serotonin 5-hydroxytryptamine (5-HT) is a key neurotransmitter for the modulation
and/or regulation of numerous physiological processes and psychiatric disorders (eg …

Is a new paradigm needed to explain how inhaled anesthetics produce immobility?

EI Eger, DE Raines, SL Shafer… - Anesthesia & …, 2008 - journals.lww.com
A paradox arises from present information concerning the mechanism (s) by which inhaled
anesthetics produce immobility in the face of noxious stimulation. Several findings, such as …

Relevance of dorsomedial hypothalamus, dorsomedial division of the ventromedial hypothalamus and the dorsal periaqueductal gray matter in the organization of …

F Ullah, T dos Anjos-Garcia, IR dos Santos… - Behavioural Brain …, 2015 - Elsevier
Electrical stimulation of the periaqueductal gray matter and ventromedial hypothalamus in
humans showed the involvement of both these structures in panic attacks. The aim of this …