Potential of zerumbone as an anti-cancer agent

S Girisa, B Shabnam, J Monisha, L Fan, CE Halim… - Molecules, 2019 - mdpi.com
Cancer is still a major risk factor to public health globally, causing approximately 9.8 million
deaths worldwide in 2018. Despite advances in conventional treatment modalities for cancer …

Natural compounds as pharmaceuticals: the key role of cytochromes P450 reactivity

G Di Nardo, G Gilardi - Trends in Biochemical Sciences, 2020 - cell.com
The design of drugs from natural products is a re-emerging area due to the need for
bioactive compounds. The exploitation of natural products and their derivatives obtained by …

[HTML][HTML] The effects of ginger and its constituents in the prevention of metabolic syndrome: A review

S Salaramoli, S Mehri, F Yarmohammadi… - Iranian Journal of …, 2022 - ncbi.nlm.nih.gov
Metabolic syndrome is a multifactorial disorder characterized by hyperglycemia,
hyperlipidemia, obesity, and hypertension risk factors. Moreover, metabolic syndrome is the …

Recent advances of analogues of curcumin for treatment of cancer

S Zhao, C Pi, Y Ye, L Zhao, Y Wei - European Journal of Medicinal …, 2019 - Elsevier
Curcumin (CU), an edible natural pigment from Curcuma Longa, has demonstrated
extensive anti-tumor effect in vivo and in vitro. With the property of reversing drug resistance …

Optimization of an Ultrasound-Assisted Extraction Method for the Extraction of Gingerols and Shogaols from Ginger (Zingiber officinale)

M Gonzalez-Gonzalez, BJ Yerena-Prieto, C Carrera… - Agronomy, 2023 - mdpi.com
The goal of this study is to optimize a UAE method for the extraction of the main bioactive
compounds present in the ginger rhizome (gingerols and shogaols). Ginger rhizome …

Electrophilic Compounds in the Human Diet and Their Role in the Induction of the Transcription Factor NRF2

CMC Andrés, JM Pérez de la Lastra… - International Journal of …, 2024 - mdpi.com
The phrase “Let food be thy medicine…” means that food can be a form of medicine and
medicine can be a form of food; in other words, that the diet we eat can have a significant …

Zerumbone Protects against Carbon Tetrachloride (CCl4)-Induced Acute Liver Injury in Mice via Inhibiting Oxidative Stress and the Inflammatory Response: Involving …

M Wang, J Niu, L Ou, B Deng, Y Wang, S Li - Molecules, 2019 - mdpi.com
The natural compound Zerumbone (hereinafter referred to as ZER), a monocyclic
sesquiterpenoid, has been reported to possess many pharmacological properties, including …

Tumor-inhibitory effects of zerumbone against HT-29 human colorectal cancer cells

F Memari, F Mirzavi, M Jalili‐Nik… - … journal of toxicology, 2022 - journals.sagepub.com
Colorectal cancer (CRC) is the second cause of cancer-associated death globally. Recently,
herbal medicinal products and, in particular, zerumbone have been widely studied and used …

Bioactive Compounds from Zingiber montanum and Their Pharmacological Activities with Focus on Zerumbone

HP Devkota, KR Paudel, MM Hassan, AI Dirar, N Das… - Applied Sciences, 2021 - mdpi.com
The genus Zingiber consists of about 85 species and many of these species are used as
food, spices, and medicines. One of the species, Zingiber montanum (J. Koenig) Link ex A …

[HTML][HTML] Understanding the mechanistic potential of plant based phytochemicals in management of postmenopausal osteoporosis

A Sharma, C Sharma, OP Shah, S Chigurupati… - Biomedicine & …, 2023 - Elsevier
Postmenopausal osteoporosis, an epidemic disorder is defined as a loss in bone mineral
density and a greater possibility of fractures in older women. It is a multifactorial disease …