The HIV/AIDS pandemic represents a major development crisis for the African continent,
which is the worst affected region in the world. Currently, almost 30 of the 42 million people …

Design: We sought to investigate the evolutionary and historical reasons for the different
epidemiological patterns of HIV-1 in the early epidemic. In order to characterize the …

BACKGROUND Human immunodeficiency virus (HIV) is a major public health concern,
particularly in Africa where HIV rates remain substantial. Pregnant women are at an …

SETTING: Randomised controlled clinical trial of Mycobacterium vaccae vaccination as an
adjunct to anti-tuberculosis treatment in human immunodeficiency virus (HIV) positive …

Integrated approaches provide better understanding of HIV/AIDS epidemics. We optimised a
multiassay algorithm (MAA) and assessed HIV incidence, correlates of recent infections …

The ability of HIV-1 to evolve resistance to antiretroviral drugs leads to treatment failure. By
nucleotide sequencing of HIV-1 subtype B isolates, amino acids responsible for drug …

Although human immunodeficiency virus type 1 (HIV-1) clade C continues to dominate the
pandemic, only two infectious clade C proviral DNA clones have been described (N …

To investigate the prevalence of subtypes A and C, and the existence of recombinants of
both subtypes in the southeast of the Democratic Republic of Congo (DRC), blood samples …

Background: A consensus conference was held to discuss priorities for antiretroviral therapy
(ART) research in Zambia, one of the world's most heavily HIV-afflicted nations. Zambia, like …

Human immunodeficiency virus type-1 (HIV-1) is a leading cause of mortality and morbidity
in the world, with almost 46 million people infected globally. HIV-1 subtype C accounts for …