Click chemistry and radiochemistry: an update

D Bauer, MA Cornejo, TT Hoang, JS Lewis… - Bioconjugate …, 2023 - ACS Publications
The term “click chemistry” describes a class of organic transformations that were developed
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …

Therapeutic targeting of senescent cells in the CNS

M Riessland, M Ximerakis, AA Jarjour… - Nature Reviews Drug …, 2024 - nature.com
Senescent cells accumulate throughout the body with advanced age, diseases and chronic
conditions. They negatively impact health and function of multiple systems, including the …

[HTML][HTML] Inflammaging and Brain Aging

MC Jurcau, A Jurcau, A Cristian, VO Hogea… - International Journal of …, 2024 - mdpi.com
Progress made by the medical community in increasing lifespans comes with the costs of
increasing the incidence and prevalence of age-related diseases, neurodegenerative ones …

Current and potential roles of immuno-PET/-SPECT in CAR T-cell therapy

A Mulgaonkar, D Udayakumar, Y Yang, S Harris… - Frontiers in …, 2023 - frontiersin.org
Chimeric antigen receptor (CAR) T-cell therapies have evolved as breakthrough treatment
options for the management of hematological malignancies and are also being developed …

Connecting epigenetics and inflammation in vascular senescence: state of the art, biomarkers and senotherapeutics

O Fraile-Martinez, D De Leon-Oliva, DL Boaru… - Frontiers in …, 2024 - frontiersin.org
Vascular diseases pose major health challenges, and understanding their underlying
molecular mechanisms is essential to advance therapeutic interventions. Cellular …