Production of antiviral “OP7 chimera” defective interfering particles free of infectious virus
L Pelz, T Dogra, P Marichal-Gallardo, MD Hein… - Applied Microbiology …, 2024 - Springer
Defective interfering particles (DIPs) of influenza A virus (IAV) are suggested for use as
broad-spectrum antivirals. We discovered a new type of IAV DIP named “OP7” that carries …
broad-spectrum antivirals. We discovered a new type of IAV DIP named “OP7” that carries …
Mathematical model calibrated to in vitro data predicts mechanisms of antiviral action of the influenza defective interfering particle “OP7”
D Rüdiger, J Piasecka, J Küchler, C Pontes, T Laske… - Iscience, 2024 - cell.com
Defective interfering particles (DIPs) are regarded as potent broad-spectrum antivirals. We
developed a mathematical model that describes intracellular co-infection dynamics of …
developed a mathematical model that describes intracellular co-infection dynamics of …
Exploring the mechanisms of interference, persistence and antiviral potential of defective interfering particles
M Bora, M Manu, M Karki - Discover Viruses, 2025 - Springer
Defective interfering particles (DIPs) were first described by Preben von Magnus as a non-
infectious form of influenza virus arising due to undiluted passages of the virus in …
infectious form of influenza virus arising due to undiluted passages of the virus in …