Two recent articles, one by Vandenbroucke, Broadbent and Pearce (henceforth VBP) 1 and
the other by Krieger and Davey Smith (henceforth KDS), 2 criticize what these two sets of …

Background: Higher plasma concentrations of the vitamin B-6 marker pyridoxal 5′-
phosphate (PLP) have been associated with reduced colorectal cancer (CRC) risk …

Objectives A recent paper by Doi et al. advocated completely replacing the relative risk (RR)
with the odds ratio (OR) as the effect measure in clinical trials and meta-analyses with binary …

Introduction: Low birth weight was defined as weight at birth less than 2500 grams. This had
numerous negative outcomes such as fetal and neonatal mortality and morbidity. It was …

Background: Despite extensive study, the role of folate in colorectal cancer remains unclear.
Research has therefore begun to address the role of other elements of the folate-methionine …

Background Evidence on the role of exogenous female sex steroid hormones in asthma
development in women remains conflicting. We sought to quantify the potential causal role …

Objectives: A recent paper by Doi et al. advocated completely replacing the relative risk (RR)
with the odds ratio (OR) as the effect measure used to report the association between a …

Aims/hypothesis Our aim was to investigate the association between birthweight and latent
autoimmune diabetes in adults (LADA), a common diabetes form with features of both type 1 …

This paper investigates if the effect of type 1 diabetes mellitus (T1DM) on school
performance, documented in prior research, has changed in more recent birth cohorts of …

Estimating the causal effects of health policy interventions is crucial for policymaking but is
challenging when using real‐world administrative health care data due to a lack of …