Depression and fatigue are conditions responsible for heavy global societal burden,
especially in patients already suffering from chronic diseases. These symptoms have been …

Major depressive disorder is the most common mental disorder with significant economic
burden and limited treatments. Acupuncture has emerged as a promising non …

Background Hippocampal enlargements are commonly reported after electroconvulsive
therapy (ECT). To clarify mechanisms, we examined if ECT-induced hippocampal volume …

Adenosine receptor subtypes, first described 40 years ago, are known to regulate diverse
biological functions and have a role in various conditions, such as cerebral and cardiac …

Clozapine is superior to other antipsychotics as a therapy for treatment-resistant
schizophrenia and schizoaffective disorder with increased risk of suicidal behavior. This …

There is a strong medical need to develop suitable biomarkers to improve the diagnosis and
treatment of depression, particularly in predicting response to certain therapeutic …

Electroconvulsive therapy (ECT) is an effective therapy for depression, but its cellular effects
on the human brain remain elusive. In rodents, electroconvulsive shocks increase …

Electroconvulsive therapy (ECT) is of the most effective treatments available for treatment-
resistant depression, yet it is underutilized in part due to its reputation of causing cognitive …

Aims Recently numerous studies have demonstrated that neuroinflammation plays a critical
role in the pathogenesis of depression. Repetitive transcranial magnetic stimulation (rTMS) …

Background Increases in the volume of the amygdala and hippocampus after
electroconvulsive therapy (ECT) are among the most robust effects known to the brain …