Nicotine: From discovery to biological effects

L Sansone, F Milani, R Fabrizi, M Belli… - International Journal of …, 2023 - mdpi.com
Nicotine, the primary psychoactive agent in tobacco leaves, has led to the widespread use of
tobacco, with over one billion smokers globally. This article provides a historical overview of …

[HTML][HTML] SARS-CoV-2 and the central nervous system: emerging insights into hemorrhage-associated neurological consequences and therapeutic considerations

J Mitra, M Kodavati, VE Provasek, KS Rao… - Ageing Research …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) continues to impact our lives by causing …

α7-and α9-containing nicotinic acetylcholine receptors in the functioning of immune system and in pain

I Shelukhina, A Siniavin, I Kasheverov… - International Journal of …, 2023 - mdpi.com
Nicotinic acetylcholine receptors (nAChRs) present as many different subtypes in the
nervous and immune systems, muscles and on the cells of other organs. In the immune …

SARS-CoV-2 nucleocapsid protein, rather than spike protein, triggers a cytokine storm originating from lung epithelial cells in patients with COVID-19

YC Wang, CH Tsai, YC Wang, LC Yen, YW Chang… - Infection, 2024 - Springer
Purpose The aim of this study was to elucidate the factors associated with severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) that may initiate cytokine cascades and …

[HTML][HTML] Plasma ACE2 species are differentially altered in COVID‐19 patients

MS García‐Ayllón, O Moreno‐Pérez… - The FASEB …, 2021 - ncbi.nlm.nih.gov
Studies are needed to identify useful biomarkers to assess the severity and prognosis of
COVID‐19 disease, caused by severe acute respiratory syndrome coronavirus (SARS‐CoV …

Smoking status, nicotine medication, vaccination, and COVID-19 hospital outcomes: findings from the COVID EHR cohort at the university of wisconsin (CEC-UW) …

TM Piasecki, SS Smith, TB Baker… - Nicotine and …, 2023 - academic.oup.com
Introduction Available evidence is mixed concerning associations between smoking status
and COVID-19 clinical outcomes. Effects of nicotine replacement therapy (NRT) and …

E-cigarettes and youth: an unresolved Public Health concern

F Virgili, R Nenna, S Ben David, E Mancino… - Italian journal of …, 2022 - Springer
The use of electronic cigarettes (e-cigarette) and vaping devices started as a potential aid for
cessation and reducing the harmful consequences of cigarette smoking, mainly in the adult …

[HTML][HTML] The influence of provaping “gatewatchers” on the dissemination of COVID-19 misinformation on Twitter: analysis of Twitter discourse regarding nicotine and …

N Silver, E Kierstead, G Kostygina, H Tran… - Journal of Medical …, 2022 - jmir.org
Background There is a lot of misinformation about a potential protective role of nicotine
against COVID-19 spread on Twitter despite significant evidence to the contrary. We need to …

Gender and genetic factors impacting COVID-19 severity

J Ranjan, A Ravindra, B Mishra - Journal of Family Medicine and …, 2021 - journals.lww.com
COVID-19 pandemic is a cause of global concern and is impacting lives and economy
globally. Infection due to SARS-CoV-2 leads to varied clinical manifestations, which can vary …

New insights into how popular electronic cigarette aerosols and aerosol constituents affect SARS-CoV-2 infection of human bronchial epithelial cells

R Phandthong, M Wong, A Song, T Martinez… - Scientific Reports, 2023 - nature.com
The relationship between the use of tobacco products and SARS-CoV-2 infection is poorly
understood and controversial. Few studies have examined the effect of electronic cigarettes …