Subversion of the actin cytoskeleton during viral infection

MP Taylor, OO Koyuncu, LW Enquist - Nature Reviews Microbiology, 2011 - nature.com
Viral infection converts the normal functions of a cell to optimize viral replication and virion
production. One striking observation of this conversion is the reconfiguration and …

Properties and functions of the nucleocapsid protein in virus assembly

D Muriaux, JL Darlix - RNA biology, 2010 - Taylor & Francis
HIV-1 nucleocapsid protein (NC) is a small basic protein generated by the cleavage of the
Gag structural polyprotein precusor by the viral protease during virus assembly in the …

Actin dynamics in host–pathogen interaction

TEB Stradal, M Schelhaas - FEBS letters, 2018 - Wiley Online Library
The actin cytoskeleton and Rho GTP ase signaling to actin assembly are prime targets of
bacterial and viral pathogens, simply because actin is involved in all motile and membrane …

Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA

YN Friew, V Boyko, WS Hu, VK Pathak - Retrovirology, 2009 - Springer
Background Host restriction factor APOBEC3G (A3G) blocks human immunodeficiency virus
type 1 (HIV-1) replication by G-to-A hypermutation, and by inhibiting DNA synthesis and …

Involvement of the Rac1-IRSp53-Wave2-Arp2/3 signaling pathway in HIV-1 Gag particle release in CD4 T cells

A Thomas, C Mariani-Floderer… - Journal of …, 2015 - Am Soc Microbiol
During HIV-1 assembly, the Gag viral proteins are targeted and assemble at the inner leaflet
of the cell plasma membrane. This process could modulate the cortical actin cytoskeleton …

Features, processing states, and heterologous protein interactions in the modulation of the retroviral nucleocapsid protein function

G Mirambeau, S Lyonnais, RJ Gorelick - RNA biology, 2010 - Taylor & Francis
Retroviral nucleocapsid (NC) is central to viral replication. Nucleic acid chaperoning is a key
function for NC through the action of its conserved basic amino acids and zinc-finger …

Retroviral matrix and lipids, the intimate interaction

E Hamard-Peron, D Muriaux - Retrovirology, 2011 - Springer
Retroviruses are enveloped viruses that assemble on the inner leaflet of cellular
membranes. Improving biophysical techniques has recently unveiled many molecular …

Sequential trafficking of Env and Gag to HIV-1 T cell virological synapses revealed by live imaging

L Wang, S Izadmehr, E Kamau, XP Kong, BK Chen - Retrovirology, 2019 - Springer
Background HIV infection is enhanced by cell adhesions that form between infected and
uninfected T cells called virological synapses (VS). VS are initiated by an interaction …

Phosphoinositides direct equine infectious anemia virus gag trafficking and release

F Fernandes, K Chen, LS Ehrlich, J Jin, MH Chen… - Traffic, 2011 - Wiley Online Library
Phosphatidylinositol 4, 5‐biphosphate [PI (4, 5) P2], the predominant phosphoinositide (PI)
on the plasma membrane, binds the matrix (MA) protein of human immunodeficiency virus …

Function of a retrotransposon nucleocapsid protein

SB Sandmeyer, KA Clemens - RNA biology, 2010 - Taylor & Francis
Long terminal repeat (LTR) retrotransposons are not only the ancient predecessors of
retroviruses, but they constitute significant fractions of the genomes of many eukaryotic …