Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …

Phthalates are pervasive compounds, and due to the ubiquitous usage of phthalates,
humans or even children are widely exposed to them. Since phthalates are not chemically …

Leydig cells are essential for steroidogenesis and spermatogenesis. An imbalance in the
production of reactive oxygen species (ROS) and the cellular antioxidant level brings about …

Male reproductive health has deteriorated considerably in the last few decades. Nutritional,
socioeconomic, lifestyle and environmental factors (among others) have been attributed to …

Infertility is one of the major health problems that affect human sociocultural life. It affects 8–
15% of couples around the world, and about 50% of infertility cases are attributed to male …

Background: The relation between persistent environmental chemicals and semen quality is
evolving, although limited data exist for men recruited from general populations. Objectives …

Maintaining the integrity of sperm DNA is vital to reproduction and male fertility. Sperm
contain a number of molecules and pathways for the repair of base excision, base …

Lindane, an organochlorine pesticide, is known to impair testicular functions and fertility. To
elucidate the mechanism (s) underpinning the gonadal effects of lindane, we sought to …

Exposure of humans and wildlife to pollutants released in the environment is a centre of
attention nowadays. Many of these chemicals (generally referred to as environmental …

Ethylene glycol monomethyl ether (EGME) is a major component of paints, lacquers, inks,
and automobile brake fluids. As a result, exposures to humans are inevitable. We therefore …