Hydrogels are three-dimensional hydrophilic polymeric networks, capable of absorbing
large quantities of water and biological fluids and simulating biological tissue when swollen …

This review focuses on a somewhat unexplored strand of regenerative medicine, that is in
situ tissue engineering. In this approach manufactured scaffolds are implanted in the injured …

In contrast to non-mammalian vertebrates, mammals and humans have limited innate
capacity for the self-regeneration of tissues and organs owing to differences in genetics …

The field of tissue engineering has made steady progress in translating various tissue
applications. Although the classical tissue engineering strategy, which involves the use of …

The controlled delivery of growth factors is a very challenging task because many different
issues have to be addressed to develop the best suited system. A wide range of approaches …

This review explores the application of hydrogels in orthopaedic clinical situations which
may benefit from enhanced growth factor delivery and improved osteogenesis of bone graft …

Bone defects caused by injury, disease, or congenital deformity remain a major health
concern, and efficiently regenerating bone is a prominent clinical demand worldwide …

Growth factors are soluble secreted proteins capable of affecting a variety of cellular
processes important for tissue regeneration. Consequently, the self-healing capacity of …

Bone is a metabolically active organ that undergoes continuous remodeling throughout life.
However, many complex skeletal defects such as large traumatic bone defects or extensive …

Hydrogels are polymeric networks with tridimensional structure, which are able to load water
and other substances. Such property makes hydrogels suitable for innumerous applications …