Evolutionary changes on the way to clathrin-mediated endocytosis in animals

M Dergai, A Iershov, O Novokhatska… - Genome biology and …, 2016 - academic.oup.com
Endocytic pathways constitute an evolutionarily ancient system that significantly contributed
to the eukaryotic cell architecture and to the diversity of cell type–specific functions and …

A large-scale computational screen identifies strong potential inhibitors for disrupting SARS-CoV-2 S-protein and human ACE2 interaction

A Singh, R Dhar - Journal of Biomolecular Structure and Dynamics, 2022 - Taylor & Francis
SARS-CoV-2 has infected millions of individuals across the globe and has killed over 2.7
million people. Even though vaccines against this virus have recently been introduced, the …

[PDF][PDF] Virtual laboratory MolDynGrid as a part of scientific infrastructure for biomolecular simulations

A Salnikov, I Sliusar, O Sudakov… - … Journal of Computing, 2010 - researchgate.net
Virtual laboratory MolDynGrid has been established for computational researches in
structural biology and bioinformatics, especially for molecular dynamics (MD) simulations of …

Optimization of grid-less scattering compensation in X-ray imaging: Simulation study

AY Danyk, SP Radchenko… - 2017 IEEE 37th …, 2017 - ieeexplore.ieee.org
Image procession algorithms for compensation of scattered radiation influence in X-ray
imaging were proposed, studied and optimized by numerical simulations. The algorithms …

Distributed system for sampling and analysis of electroencephalograms

O Sudakov, G Kriukova, R Natarov… - 2017 9th IEEE …, 2017 - ieeexplore.ieee.org
Distributed system for sampling and analysis of electroencephalograms is proposed and
implemented in alpha state. The system is based on the previously developed database for …

Asymmetric structure and domain binding interfaces of human tyrosyl‐tRNA synthetase studied by molecular dynamics simulations

OV Savytskyi, SO Yesylevskyy… - Journal of Molecular …, 2013 - Wiley Online Library
Human tyrosyl‐tRNA synthetase (HsTyrRS) is composed of two structural modules: N‐
terminal catalytic core and an EMAP II‐like C‐terminal domain. The structures of these …

Integrated tools for molecular dynamics simulation data analysis in the MolDynGrid virtual laboratory

OV Savytskyi, IA Sliusar… - Proceedings of the …, 2011 - ieeexplore.ieee.org
Existing molecular modeling software and different techniques of molecular dynamics
trajectories analysis were evaluated in terms of subsequent integration into the MolDynGrid …

Integrated grid environment for massive distributed computing in neuroscience

A Salnikov, R Levchenko… - Proceedings of the 6th …, 2011 - ieeexplore.ieee.org
Automation methods for huge amount of computations in grid environment and their
applications in Ukrainian National Grid (UNG) are described. Proposed methods are based …

Computational modeling and molecular dynamics simulations of mammalian cytoplasmic tyrosyl-tRNA synthetase and its complexes with substrates

VO Kravchuk, OV Savytskyi, KO Odynets… - Journal of …, 2017 - Taylor & Francis
Cytoplasmic tyrosyl-tRNA synthetase (TyrRS) is one of the key enzymes of protein
biosynthesis. TyrRSs of pathogenic organisms have gained attention as potential targets for …

Interdomain compactization in human tyrosyl-tRNA synthetase studied by the hierarchical rotations technique

SO Yesylevskyy, OV Savytskyi, KA Odynets… - Biophysical …, 2011 - Elsevier
Aminoacyl-tRNA synthetases are key enzymes of protein biosynthesis which usually
possess multidomain structures. Mammalian tyrosyl-tRNA synthetase is composed of two …