Oncogenic role of tumor necrosis factor α-induced protein 8 (TNFAIP8)

S Niture, X Dong, E Arthur, U Chimeh, SS Niture… - Cells, 2018 - mdpi.com
Tumor necrosis factor (TNF)-α-induced protein 8 (TNFAIP8) is a founding member of the
TIPE family, which also includes TNFAIP8-like 1 (TIPE1), TNFAIP8-like 2 (TIPE2), and …

[HTML][HTML] Tumor necrosis factor-α induced protein 8: pathophysiology, clinical significance, and regulatory mechanism

L Zhang, R Liu, Y Luan, Y Yao - International Journal of Biological …, 2018 - ncbi.nlm.nih.gov
Tumor necrosis factor-α-induced protein-8 (TNFAIP8) is the earliest discovered component
of TNFAIP8 family [tumor necrosis factor-α-induced protein-8 like (TIPE) family]. TNFAIP8 …

TNFAIP8 regulates autophagy, cell steatosis, and promotes hepatocellular carcinoma cell proliferation

S Niture, MA Gyamfi, M Lin, U Chimeh, X Dong… - Cell death & …, 2020 - nature.com
Tumor necrosis factor-α-induced protein 8 (TNFAIP8) expression has been linked to tumor
progression in various cancer types, but the detailed mechanisms of TNFAIP8 are not fully …

Genetic variation of macronutrient tolerance in Drosophila melanogaster

E Havula, S Ghazanfar, N Lamichane, D Francis… - Nature …, 2022 - nature.com
Carbohydrates, proteins and lipids are essential nutrients to all animals; however, closely
related species, populations, and individuals can display dramatic variation in diet. Here we …

[HTML][HTML] TNFAIP8 promotes prostate cancer cell survival by inducing autophagy

S Niture, M Ramalinga, H Kedir, D Patacsil, SS Niture… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Tumor necrosis factor-α-inducible protein 8 (TNFAIP8) is a TNF-α inducible anti-apoptotic
protein with multiple roles in tumor growth and survival. Mechanisms of cell survival by …

The Tnfaip8-PE complex is a novel upstream effector in the anti-autophagic action of insulin

JS Kim, J Park, MS Kim, JY Ha, YW Jang, DH Shin… - Scientific reports, 2017 - nature.com
Defective hepatic autophagy is observed in obesity and diabetes, whereas autophagy is
inhibited by insulin in hepatocytes. Insulin-induced anti-autophagy is mediated by non …

Dysfunction of lipid storage droplet-2 suppresses endoreplication and induces JNK pathway-mediated apoptotic cell death in Drosophila salivary glands

TD Binh, YDH Nguyen, TLA Pham, K Komori… - Scientific reports, 2022 - nature.com
The lipid storage droplet-2 (LSD-2) protein of Drosophila is a homolog of mammalian
perilipin 2, which is essential for promoting lipid accumulation and lipid droplet formation …

TIPE2 suppressed cisplatin resistance by inducing autophagy via mTOR signalling pathway

H Guo, H Ren, J Li, M Hao, J Hao, H Ren, L Guo… - … and molecular pathology, 2020 - Elsevier
Tumour necrosis factor-α-induced protein-8-like-2 (TIPE2) has been associated with the
progression of numerous cancers. Cisplatin, as a classical chemotherapy strategy for …

Drosophila HUWE1 Ubiquitin Ligase Regulates Endoreplication and Antagonizes JNK Signaling During Salivary Gland Development

Y Yanku, E Bitman-Lotan, Y Zohar, E Kurant, N Zilke… - Cells, 2018 - mdpi.com
The HECT-type ubiquitin ligase HECT, UBA and WWE Domain Containing 1,(HUWE1)
regulates key cancer-related pathways, including the Myc oncogene. It affects cell …

A novel TNFAIP8 gene mediates l-arginine metabolism in Apostichopus japonicus

Y Shao, H Chen, M Lv, C Li, W Zhang, Y Li… - Fish & shellfish …, 2017 - Elsevier
Tumor necrosis factor (TNF)-α-induced protein 8 (TNFAIP8) family is a newly identified
protein with vital roles in maintaining immune homeostasis. In the current study, we first …