Over time, organisms have evolved strategies to cope with the abundance of dioxygen on Earth. Oxygen-utilizing enzymes tightly control the reactions involving O2 mostly by …
E Chovancova, A Pavelka, P Benes, O Strnad… - 2012 - journals.plos.org
Tunnels and channels facilitate the transport of small molecules, ions and water solvent in a large variety of proteins. Characteristics of individual transport pathways, including their …
Enzymes are very efficient catalysts that are essential for the functioning of living organisms. The low efficiency of biocatalysts produced de novo relative to those that have evolved …
A Mattevi - Trends in biochemical sciences, 2006 - cell.com
Flavin-dependent enzymes catalyse a wide range of reactions and, thereby, facilitate a variety of cellular processes. Among the properties that equip flavoenzymes with this …
The flavoenzyme nicotine oxidoreductase (NicA2) is a promising injectable treatment to aid in the cessation of smoking, a behavior responsible for one in ten deaths worldwide. NicA2 …
JL García, I Uhía, B Galán - Microbial biotechnology, 2012 - Wiley Online Library
Cholesterol is a steroid commonly found in nature with a great relevance in biology, medicine and chemistry, playing an essential role as a structural component of animal cell …
This review provides an overview of oxidases that utilise a flavin cofactor for catalysis. This class of oxidative flavoenzymes has shown to harbour a large number of biotechnologically …
Many enzymes use one or more cofactors, such as biotin, heme, or flavin. These cofactors may be bound to the enzyme in a noncovalent or covalent manner. Although most …
Abstract Alcohol oxidases (Alcohol: O 2 Oxidoreductase; EC 1.1. 3. x) are flavoenzymes that catalyze the oxidation of alcohols to the corresponding carbonyl compounds with a …