Drug development is a lengthy and costly process that proceeds through several stages
from target identification to lead discovery and optimization, preclinical validation and …

In tissue engineering and regenerative medicine, a biomaterial provides mechanical support
and biochemical signals to encourage cell attachment and modulate cell behaviour …

The implementation of microfluidic devices within life sciences has furthered the possibilities
of both academic and industrial applications such as rapid genome sequencing, predictive …

Regenerative medicine and tissue engineering strategies have made remarkable progress
in remodeling, replacing, and regenerating damaged cardiovascular tissues. The design of …

Two-photon lithography is a laser writing technique that can produce 3D microstructures
with resolutions below the diffraction limit. This review focuses on its applications to study …

Summary Discoidin domain receptor 1 (DDR1) is a tyrosine kinase collagen adhesion
receptor that mediates cell migration through association with non-muscle myosin IIA …

The mechanical properties of tumors and the tumor environment provide important
information for the progression and characterization of cancer. Tumors are surrounded by an …

Renal disease represents a major health problem that often results in end-stage renal failure
necessitating dialysis and eventually transplantation. Historically these diseases have been …

The extracellular matrix (ECM)‐regulated phenotypic plasticity is crucial for metastatic
progression of triple negative breast cancer (TNBC). While ECM faithful cell‐based models …

Current in vitro models fall short in deciphering the mechanisms of cardiac hypertrophy
induced by volume overload. We developed a pneumatic microfluidic platform for high …