Glucose and related sugars repress the transcription of genes encoding enzymes required
for the utilization of alternative carbon sources; some of these genes are also repressed by …

Glucose, the most abundant monosaccharide in nature, is the principal carbon and energy
source for nearly all cells. The first, and rate-limiting, step of glucose metabolism is its …

Glucose has dramatic effects on the regulation of carbon metabolism and on many other
properties of yeast cells. Several sensing and signalling pathways are involved. For many …

Transport across the plasma membrane is the first, obligatory step of hexose utilization. In
yeast cells the uptake of hexoses is mediated by a large family of related transporter …

It has been known for a long time that yeast are capable of making rapid metabolic
adjustments in response to changing extracellular nutrient conditions. Until recently it was …

Heterotrophic organisms rely on the ingestion of organic molecules or nutrients from the
environment to sustain energy and biomass production. Non-motile, unicellular organisms …

The Std1 protein modulates the expression of glucose-regulated genes, but its exact
molecular role in this process is unclear. A two-hybrid screen for Std1-interacting proteins …

We have determined that the mutant genes DGT1‐1 and BPC1‐1, which impair glucose
transport and catabolite repression in Saccharomyces cerevisiae, are allelic forms of MTH1 …

Transcriptional regulation in yeast involves a number of general trans‐acting factors
affecting chromatin structure. The Swi–Snf complex is required for expression of a large …

Saccharomyces cerevisiae HTR1 mutants are severely impaired in the uptake of glucose.
We have cloned dominant HTR1 mutant alleles and show that they encode mutant forms of …